Evidence map›Paper›PMID 38952234›Full record

ReviewLab on a chip2024

Sample preparation and detection methods in point-of-care devices towards future at-home testing.

George Adedokun, Morteza Alipanah, Z Hugh Fan

Abstract readReview
In one paragraph

Review in Lab on a chip, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Rapid detection of theOpen life sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

George AdedokunInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, P.O. Box 116250, Gainesville, FL 32611, USA. hfan@ufl.edu.ORCID 0000-0002-7079-0963
Morteza AlipanahInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, P.O. Box 116250, Gainesville, FL 32611, USA. hfan@ufl.edu.
Z Hugh FanInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, P.O. Box 116250, Gainesville, FL 32611, USA. hfan@ufl.edu.ORCID 0000-0002-1812-8016

Funding

Multiplexed Airborne Virus Collection and Detection at the Point-of-CareR01AI158868 · NIAID · UNIVERSITY OF FLORIDA · PI FAN, Z. HUGH · 2021 to 2025
$1.6M
Multiplexed Detection of Mosquito-Borne Viruses at the Point-of-CareR01AI155735 · NIAID · UNIVERSITY OF FLORIDA · PI FAN, Z. HUGH · 2021 to 2024
$1.5M
NIAID NIH HHS R01 AI155735NIAID NIH HHS R01 AI158868
6 · The paper itself

Abstract

Timely and accurate diagnosis is critical for effective healthcare, yet nearly half the global population lacks access to basic diagnostics. Point-of-care (POC) testing offers partial solutions by enabling low-cost, rapid diagnosis at the patient's location. At-home POC devices have the potential to advance preventive care and early disease detection. Nevertheless, effective sample preparation and detection methods are essential for accurate results. This review surveys recent advances in sample preparation and detection methods at POC. The goal is to provide an in-depth understanding of how these technologies can enhance at-home POC devices. Lateral flow assays, nucleic acid tests, and virus detection methods are at the forefront of POC diagnostic technology, offering rapid and sensitive tools for identifying and measuring pathogens, biomarkers, and viral infections. By illuminating cutting-edge research on assay development for POC diagnostics, this review aims to accelerate progress towards widely available, user-friendly, at-home health monitoring tools that empower individuals in personalized healthcare in the future.

Indexed as

Point-of-Care SystemsPoint-of-Care TestingHumansLab-On-A-Chip DevicesSpecimen Handling

Identifiers

PMID38952234
PMCPMC11270053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.