Evidence map›Paper›PMID 38952067›Full record

ArticleJournal of applied clinical medical physics2024

Dosimetric impact of the respiratory motion of the liver dome in stereotactic body radiotherapy for spine metastasis: A planning study.

Hiroyuki Okamoto, Midori Nonaka, Takahito Chiba, Tomoya Kaneda, Yuta Kobayashi, Satoshi Nakamura, Hiroki Nakayama, Kotaro Iijima, Yasunori Shuto, Miki Yonemura and 9 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hiroyuki OkamotoRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9491-787X
Midori NonakaDepartment of Radiological Technology, National Cancer Center Hospital, Tokyo, Japan.
Takahito ChibaRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6550-9727
Tomoya KanedaDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yuta KobayashiRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Satoshi NakamuraRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Hiroki NakayamaRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Kotaro IijimaRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Yasunori ShutoRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Miki YonemuraRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Riki OshikaRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Hironori KishidaRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Yuka UragoRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Masato NishitaniRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Shuka NishinaRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Takumi SakamotoRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.
Yoshihiro ShibataDepartment of Radiological Technology, National Cancer Center Hospital, Tokyo, Japan.
Tomonori GokaDepartment of Radiological Technology, National Cancer Center Hospital, Tokyo, Japan.
Hiroshi IgakiDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.

Funding

National Cancer Center Research and Development Fund 2022-A-18
6 · The paper itself

Abstract

purposeThis study aimed to clarify the dosimetric impact of the respiratory motion of the liver on stereotactic body radiation therapy (SBRT) for spine metastasis and examine the utility of introducing beam avoidance (beam-off at specific gantry angles).

methodsA total of 112 consecutive patients who underwent SBRT for spine metastasis between 2018 and 2024 were examined. Overall, 15 patients who had lesions near the liver dome were included in this study. Retrospective treatment plans were generated using computed tomography (CT) images acquired during inhalation and exhalation to evaluate the dosimetric impact of respiratory motion of the liver. The dose difference (DD) and relative value (DD%) were evaluated using the dose-volume histogram (DVH) metrics, planning target volume D

resultsThe DD in almost all DVH metrics tended to increase when the liver moved away from the target during inhalation: For example, Mean

conclusionsRespiratory motion of the liver dome can cause substantial dosimetric discrepancies in the dose delivered to the spinal cord, although the extent depends on patient variables. Dose assessment should be performed for determining the appropriate means of respiratory management, such as breath-hold. Alternatively, beam avoidance effectively mitigates the impact.

Indexed as

LiverOrgans at RiskRadiosurgeryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRespirationSpinal NeoplasmsAgedAged, 80 and overFemaleHumansMaleMiddle AgedMovementPrognosisdosimetric impactSBRTspine metastasis

Identifiers

PMID38952067
PMCPMC11492324

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.