Evidence map›Paper›PMID 38951949›Full record

ArticleGlobal health research and policy2024

Strengthening access to cancer medicines for children in East Africa: policy options to enhance medicine procurement, forecasting, and regulations.

Kadia Petricca, Laura Carson, Joyce Kambugu, Avram Denburg

Abstract read
In one paragraph

Article in Global health research and policy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kadia PetriccaPeter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Laura CarsonPeter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Joyce KambuguDepartment of Paediatric Oncology, Uganda Cancer Institute, Kampala, Uganda.
Avram DenburgDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada. avram.denburg@sickkids.ca.ORCID 0000-0003-0039-0742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gaps in access to quality essential medicines remain a major impediment to the effective care of children with cancer in low-and middle-income countries (LMICs). The World Health Organization reports that less than 30% of LMICs have consistent availability of childhood cancer medicines, compared to over 95% in high-income countries. Information provided within this policy brief is drawn from a review of the literature and a mixed-methods study published in the Lancet Oncology that analyzed determinants of cancer medicine access for children in Kenya, Tanzania, Uganda, and Rwanda. Three key policy options are presented to guide strategic policy direction and critical health system planning for strengthening access to cancer medicines for children: pooled procurement, evidence-based forecasting, and regional harmonization of regulatory processes. Enhancing regional pooled procurement to address fragmented markets and improve medicine supply, investing in health information systems for improved forecasting and planning of childhood cancer medicine needs, and promoting regulatory harmonization to streamline medicine approval and quality assurance across East Africa are recommended. This policy brief is intended for policymakers, clinicians, and health-system planners involved in the procurement, supply chain management, policy and financing of childhood cancer medicines.

Indexed as

Antineoplastic AgentsHealth PolicyHealth Services AccessibilityNeoplasmsAfrica, EasternChildDeveloping CountriesDrugs, EssentialForecastingHumansAntineoplastic AgentsDrugs, EssentialAccess to medicinesChildhood cancerPolicy briefPooled procurementRegional harmonization

Identifiers

PMID38951949
PMCPMC11218261

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.