ArticleCommunications biology2024
Continent-wide genomic analysis of the African buffalo (Syncerus caffer).
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A practical framework for identifying genetic subpopulations and ESUs: Insights for IUCN assessments and broader management.Bioscience · 2026Article
- Unlocking the African bioeconomy and strengthening biodiversity conservation through genomics and bioinformatics.npj biodiversity · 2025Review
- The evolution and convergence of mutation spectra across mammals.Communications biology · 2025Article
- Article
- Genome-wide diversity, population structure and signatures of inbreeding in the African buffalo in Mozambique.BMC ecology and evolution · 2024Article
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Authors and funding
30 authors.
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Abstract
The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis can provide insights into the evolutionary history of the species, and the key selective pressures shaping populations, including assessment of population level differentiation, population fragmentation, and population genetic structure. In this study we generated the highest quality de novo genome assembly (2.65 Gb, scaffold N50 69.17 Mb) of African buffalo to date, and sequenced a further 195 genomes from across the species distribution. Principal component and admixture analyses provided little support for the currently described four subspecies. Estimating Effective Migration Surfaces analysis suggested that geographical barriers have played a significant role in shaping gene flow and the population structure. Estimated effective population sizes indicated a substantial drop occurring in all populations 5-10,000 years ago, coinciding with the increase in human populations. Finally, signatures of selection were enriched for key genes associated with the immune response, suggesting infectious disease exert a substantial selective pressure upon the African buffalo. These findings have important implications for understanding bovid evolution, buffalo conservation and population management.
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