ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2024
Interaction of perceived social support and childhood maltreatment on limbic responsivity towards negative emotional stimuli in healthy individuals.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Childhood Trauma and Adult Loneliness as Predictors of Sleep Health in Blackfeet American Indian Adults.International journal of behavioral medicine · 2026Article
- Childhood trauma and impulsivity in children with first-episode depression: mediation by left frontopolar thickness.BMC psychiatry · 2026Article
- Changes in brain function during negative emotion processing following cognitive-behavioural therapy in depressive disorders.The British journal of psychiatry : the journal of mental science · 2026Article
- The impact of perceived social support on children's problem behaviors: the parallel mediating roles of attentional bias.BMC psychology · 2025Article
- Factors associated with social alienation in cancer patients: a structural equation modeling approach.Frontiers in psychology · 2025Article
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15 authors.
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Abstract
Childhood maltreatment (CM) is associated with increased limbic activity, while social support is linked to decreased limbic activity towards negative stimuli. Our study aimed to explore the interaction of perceived social support with CM, and their combined impact on limbic activity in negative emotion processing. A total of 130 healthy individuals (HC) underwent a negative emotional face processing paradigm. They were divided into two groups based on the Childhood Trauma Questionnaire: n = 65 HC without CM matched with n = 65 HC with CM. In a region-of-interest approach of the bilateral amygdala-hippocampus-complex (AHC), regression analyses investigating the association of CM and perceived social support with limbic activity and a social support x CM ANCOVA were conducted. CM was associated with increased AHC activity, while perceived social support tended to be associated with decreased AHC activity during negative emotion processing. The ANCOVA showed a significant interaction in bilateral AHC activity (p
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