Evidence map›Paper›PMID 38951437›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2025

Angiosarcoma: a 10-year retrospective study from a high-volume UK regional referral centre.

Ahrin Anna Morrow, James Hodson, Costanza Figura, Salena Bains, Robert M Warner, L Max Almond

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Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prognosis of primary cutaneous angiosarcoma versus radiation-induced angiosarcoma: A cohort study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahrin Anna MorrowUniversity Hospitals Birmingham NHS Trust, Birmingham, UK. anna_a_c@yahoo.com.ORCID http://orcid.org/0009-0003-9093-4201
James HodsonResearch Development and Innovation, Institute of Translational Medicine, University Hospitals Birmingham NHS Trust, Birmingham, UK.
Costanza FiguraUniversity Hospitals Birmingham NHS Trust, Birmingham, UK.
Salena BainsUniversity Hospitals Birmingham NHS Trust, Birmingham, UK.
Robert M WarnerUniversity Hospitals Birmingham NHS Trust, Birmingham, UK.
L Max AlmondUniversity Hospitals Birmingham NHS Trust, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAngiosarcoma (AS) is a rare malignancy with considerable heterogeneity seen in its aetiology, anatomical location, and clinicopathological behaviour. Diagnosis is often delayed and prognosis poor. The purpose of this study was to perform a retrospective review of all cases of AS over 10 years at a high-volume regional UK referral centre. METHODS/PATIENTS: We reviewed all cases of AS discussed at the sarcoma multidisciplinary meetings of University Hospitals Birmingham NHS Foundation Trust from September 2013 to August 2023. Demographic and clinicopathologic features at diagnosis, approaches to treatment, and outcomes were compared between four AS subtypes.

resultsA total of 130 cases were identified. The median age at diagnosis was 71 years, with the majority being female (78%). The most common AS subtype was radiation-induced AS (RIAS) (n = 72; 55%), followed by primary cutaneous (n = 28; 22%), primary non-cutaneous (n = 25; 19%), and AS secondary to lymphoedema (n = 5; 4%). Metastases were present at diagnosis in 18% of patients. Treatment was with surgery in the majority of patients (71%). The median survival for the cohort was 30 months (95% CI 20-40), although this differed significantly by AS subtype (p < 0.001), ranging from 5 months in primary non-cutaneous AS to 76 months in RIAS.

conclusionRIAS is the most common AS subtype, with surgery the only potentially curative treatment modality. Overall prognosis varies significantly by subtype. An international consensus on classification of AS subtypes is required to allow meaningful comparisons across studies and/or a prospective multi-centre registry.

Indexed as

HemangiosarcomaAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPrognosisReferral and ConsultationRetrospective StudiesSkin NeoplasmsSurvival RateUnited KingdomAngiosarcomaCancer surgeryRadiation-induced angiosarcomaRadiation therapyRetrospective studySarcoma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.