Evidence map›Paper›PMID 38951214›Full record

ArticleMikrochimica acta2024

A cancer-targeted glutathione-gated probe for self-sufficient ST/CDT combination therapy and FRET-based miRNA imaging.

Cong Su, Simin Cheng, Ruimin Cheng, Kexin Li, Ying Li

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cong Su *Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE; Shandong Key Laboratory of Biochemical Analysis; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China.
Simin Cheng *School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China.
Ruimin ChengSchool of Economic and Management, Shanghai University of Sport, Shanghai, 200438, PR China.
Kexin LiKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE; Shandong Key Laboratory of Biochemical Analysis; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China.
Ying LiKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE; Shandong Key Laboratory of Biochemical Analysis; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China. liying79307@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cancer-targeted glutathione (GSH)-gated theranostic probe (CGT probe) for intracellular miRNA imaging and combined treatment of self-sufficient starvation therapy (ST) and chemodynamic therapy (CDT) was developed. The CGT probe is constructed using MnO

Indexed as

Fluorescence Resonance Energy TransferGlutathioneManganese CompoundsMicroRNAsOxidesAnimalsAptamers, NucleotideFluorescent DyesHumansMiceMice, Inbred BALB CMice, NudeNanostructuresNeoplasmsNucleolinOligodeoxyribonucleotidesAGRO 100Aptamers, NucleotideFluorescent DyesGlutathioneManganese Compoundsmanganese dioxideMicroRNAsMIRN21 microRNA, humanNucleolinOligodeoxyribonucleotidesOxidesDisubstituted-catalytic hairpin assemblyFRET imagingGSH-gated probeMnO2 nanosheetSelf-sufficient combination therapy

Identifiers

PMID38951214

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.