Evidence map›Paper›PMID 38951010›Full record

SynthesisBMJ open2024

Living with mesothelioma: a systematic review of mental health and well-being impacts and interventions for patients and their informal carers.

Virginia Sherborne, Stephanie Ejegi-Memeh, Angela Mary Tod, Bethany Taylor, Sarah Hargreaves, Clare Gardiner

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Virginia SherborneMesothelioma UK Research Centre, Division of Nursing and Midwifery, The University of Sheffield, Sheffield, UK h.v.sherborne@sheffield.ac.uk.ORCID 0000-0003-1106-765X
Stephanie Ejegi-MemehMesothelioma UK Research Centre, Division of Nursing and Midwifery, The University of Sheffield, Sheffield, UK.
Angela Mary TodMesothelioma UK Research Centre, Division of Nursing and Midwifery, The University of Sheffield, Sheffield, UK.ORCID 0000-0001-6336-3747
Bethany TaylorMesothelioma UK Research Centre, Division of Nursing and Midwifery, The University of Sheffield, Sheffield, UK.ORCID 0000-0003-4090-3047
Sarah HargreavesMesothelioma UK Research Centre, Division of Nursing and Midwifery, The University of Sheffield, Sheffield, UK.
Clare GardinerMesothelioma UK Research Centre, Division of Nursing and Midwifery, The University of Sheffield, Sheffield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMesothelioma is an aggressive cancer predominantly affecting the lung and abdominal linings. It can have a unique impact on mental health and well-being (MHWB) due to its incurability, poor prognosis and asbestos-exposure causation. This review's aims were to identify/synthesise international evidence on mesothelioma's MHWB impacts; explore MHWB interventions used by patients and carers; and identify evidence of their effectiveness.

designSystematic review. DATA SOURCES: Databases, searched March 2022 and March 2024, were MEDLINE; CINAHL; PsycINFO; Cochrane Library; ASSIA. ELIGIBILITY CRITERIA: We included study designs focusing on psychological impacts of living with mesothelioma and MHWB interventions used by patients and informal carers, published in English since January 2002. DATA EXTRACTION AND SYNTHESIS: A team of reviewers screened included studies using standardised methods. Quality was assessed using validated tools: Mixed-Methods Appraisal tool for primary research and Joanna Briggs Institute Critical Appraisal Checklist for Systematic Reviews.

resultsForty-eight studies met the inclusion criteria: 20 qualitative, 16 quantitative, nine reviews, two mixed-methods, one combined systematic review/qualitative study. UK studies predominated. Many MHWB impacts were reported, including traumatic stress, depression, anxiety and guilt. These were influenced by mesothelioma's causation, communication issues and carer-patient relational interactions. Participants used wide-ranging MHWB interventions, including religious/spiritual practice; talking to mental-health professionals; meaning-making. Some strategies were presented as unhelpful, for example, denial. Participants reported lack of access to support.

conclusionsMost qualitative studies were rated high quality. The quality of the quantitative studies and reviews varied. The sparse literature regarding MHWB in mesothelioma means more research is needed into impacts on patients and carers, including trauma. To enable access to evidence-based support, research is recommended concerning MHWB interventions' effectiveness in mesothelioma. PROSPERO REGISTRATION NUMBER: CRD42022302187.

Indexed as

CaregiversMental HealthMesotheliomaAnxietyDepressionHumansQuality of Lifeadult oncologymental healthrespiratory tract tumourssystematic review

Identifiers

PMID38951010
PMCPMC11218022

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.