Evidence map›Paper›PMID 38950987›Full record

ArticleBMJ open2024

Comparing performance of primary care clinicians in the interpretation of SPIROmetry with or without Artificial Intelligence Decision support software (SPIRO-AID): a protocol for a randomised controlled trial.

Gillian Doe, Ethaar El-Emir, George D Edwards, Marko Topalovic, Rachael A Evans, Richard Russell, Karl P Sylvester, Karolien Van Orshoven, Anthony P Sunjaya, David A Scott and 9 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05933694 (A Randomized Controlled Trial Comparing Performance of Primary Care Clinicians in the Interpretation of SPIROmetry With or Without Artificial Intelligence Decision Support Software), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05933694 naunknown statusnot on this map

A Randomized Controlled Trial Comparing Performance of Primary Care Clinicians in the Interpretation of SPIROmetry With or Without Artificial Intelligence Decision Support Software

TypeinterventionalSponsorRoyal Brompton & Harefield NHS Foundation TrustRan2023 to 2024Enrolled228ConditionsLung DiseaseArmsArtificial Intelligence-powered Spirometry Interpretation Report
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Gillian DoeNIHR Biomedical Research Centre, University of Leicester, Leicester, UK ged6@leicester.ac.uk.ORCID 0000-0003-4782-5811
Ethaar El-EmirHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.
George D EdwardsHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.
Marko TopalovicARTIQ, Leuven, Belgium.
Rachael A EvansNIHR Biomedical Research Centre, University of Leicester, Leicester, UK.ORCID 0000-0002-1667-868X
Richard RussellKings Centre for Lung Health, King's College London, London, UK.
Karl P SylvesterCambridge Respiratory Physiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Karolien Van OrshovenARTIQ, Leuven, Belgium.
Anthony P SunjayaHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.
David A ScottSouthampton Health Technology Assessments Centre, University of Southampton, Southampton, UK.
A Toby PrevostNightingale-Saunders Clinical Trials and Epidemiology Unit, King's College London, London, UK.ORCID 0000-0003-1723-0796
Jennifer HarveyHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.
Stephanie Jc TaylorWolfson Institute of Population Health, Queen Mary University of London, London, UK.
Nicholas S HopkinsonNational Heart and Lung Insititute, Imperial College London, London, UK.
Samantha S KonHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.
Ian JarroldAsthma and Lung UK, London, UK.
Nannette SpainPPI Partner, London, UK.
Winston BanyaHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.
William D-C ManHarefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, UK, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpirometry is a point-of-care lung function test that helps support the diagnosis and monitoring of chronic lung disease. The quality and interpretation accuracy of spirometry is variable in primary care. This study aims to evaluate whether artificial intelligence (AI) decision support software improves the performance of primary care clinicians in the interpretation of spirometry, against reference standard (expert interpretation). METHODS AND ANALYSIS: A parallel, two-group, statistician-blinded, randomised controlled trial of primary care clinicians in the UK, who refer for, or interpret, spirometry. People with specialist training in respiratory medicine to consultant level were excluded. A minimum target of 228 primary care clinician participants will be randomised with a 1:1 allocation to assess fifty de-identified, real-world patient spirometry sessions through an online platform either with (intervention group) or without (control group) AI decision support software report. Outcomes will cover primary care clinicians' spirometry interpretation performance including measures of technical quality assessment, spirometry pattern recognition and diagnostic prediction, compared with reference standard. Clinicians' self-rated confidence in spirometry interpretation will also be evaluated. The primary outcome is the proportion of the 50 spirometry sessions where the participant's preferred diagnosis matches the reference diagnosis. Unpaired t-tests and analysis of covariance will be used to estimate the difference in primary outcome between intervention and control groups. ETHICS AND DISSEMINATION: This study has been reviewed and given favourable opinion by Health Research Authority Wales (reference: 22/HRA/5023). Results will be submitted for publication in peer-reviewed journals, presented at relevant national and international conferences, disseminated through social media, patient and public routes and directly shared with stakeholders. TRIAL REGISTRATION NUMBER: NCT05933694.

Indexed as

Artificial IntelligencePrimary Health CareSpirometryDecision Support Systems, ClinicalHumansRandomized Controlled Trials as TopicSoftwareUnited Kingdomlung diseasesprimary carerespiratory medicine (see thoracic medicine)

Identifiers

PMID38950987
PMCPMC11218008

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.