Evidence map›Paper›PMID 38949723›Full record

ArticleEcotoxicology (London, England)2024

Bacterial toxicity of Acetaminophen and Edaravone, and their binary mixtures: experimental and predicted values using traditional and novel Van Laar-based models.

Iván Álvarez-Escalante, Sonia Martínez-Páramo, Rubén Irusta-Mata

Abstract read
In one paragraph

Article in Ecotoxicology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Iván Álvarez-EscalanteDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Calle Doctor Mergelina s/n, 47011, Valladolid, Spain.
Sonia Martínez-PáramoDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Calle Doctor Mergelina s/n, 47011, Valladolid, Spain.
Rubén Irusta-MataDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Calle Doctor Mergelina s/n, 47011, Valladolid, Spain. ruben.irusta@uva.es.

Funding

Junta de Castilla y León UIC 071, CLU 2017-09 and VA080G18Ministerio de Ciencia, Innovación y Universidades" of Spain CTQ2017-84006-C3-1-R
6 · The paper itself

Abstract

In recent years, the presence of Pharmaceutical Active Compounds (PhACs) in ecosystems has become a serious environmental problem due to their capacity to induce harmful effects at extremely low concentrations in both humans and wildlife. Water treatment plants have not been designed to remove these types of compounds efficiently. Thus, the detection of these pollutants is essential to evaluate their negative impacts and is one of the emerging issues in environmental chemistry. The main objective of this study is to determine the bacterial toxicity of two PhACs (both individually and as a mixture) through the quantification of bioluminescence inhibition in the marine bacteria Aliivibrio fischeri, a commonly used method in short-term toxicity tests. In this work, Acetaminophen and Edaravone, two drugs approved by the Food and Drug Administration, have been studied. The acute toxicity of these PhACs has been tested at two exposure times (5 and 15 min) and different concentrations, by estimation of the median effective concentration (EC

Indexed as

AcetaminophenAliivibrio fischeriEdaravoneWater Pollutants, ChemicalAcetaminophenEdaravoneWater Pollutants, ChemicalBinary mixturesConcentration AdditionIndependent ActionMicrotox®PharmaceuticalsVan Laar-based model

Identifiers

PMID38949723
PMCPMC11358354

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.