Evidence map›Paper›PMID 38949418›Full record

ArticleMolecular imaging and radionuclide therapy2024

Can Pantoprazole be Used for Premedication in Meckel Scintigraphy?

Aziz Gültekin, Tarık Şengöz, Samiye Demirezen, Doğangün Yüksel

Abstract read
In one paragraph

Article in Molecular imaging and radionuclide therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aziz GültekinPamukkale University Faculty of Medicine, Department of Nuclear Medicine, Denizli, Türkiye.ORCID 0000-0002-0311-8077
Tarık ŞengözPamukkale University Faculty of Medicine, Department of Nuclear Medicine, Denizli, Türkiye.ORCID 0000-0003-2621-7585
Samiye DemirezenPamukkale University Faculty of Medicine, Department of Nuclear Medicine, Denizli, Türkiye.ORCID 0000-0002-2218-8580
Doğangün YükselPamukkale University Faculty of Medicine, Department of Nuclear Medicine, Denizli, Türkiye.ORCID 0000-0003-0983-2834

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Meckel scintigraphy is used to diagnose Meckel's diverticulum. Previously, premedication with ranitidine was the most frequently used method to increase the accuracy of scintigraphy. However, ranitidine can no longer be used because it is banned by the Food and Drug Administration. The aim of this study was to investigate the usability of pantoprazole as a premedication instead of ranitidine in Meckel scintigraphy. Methods: Twelve New Zealand rabbits were used in this experimental study. Rabbits were divided into two groups: pantoprazole and control. Six rabbits were premedicated with pantoprazole for three days. Meckel scintigraphy was performed on all rabbits. Counts were made and compared by drawing regions of interest from the stomach walls. Results: According to the findings of this experimental study, pantoprazole significantly increased Tc-99m-pertechnetate uptake in the stomach of rabbits on both visual and quantitative evaluation. Conclusion: Pantoprazole increases the gastric wall uptake of Tc-99m-pertechnetate in rabbits and is a potential drug for premedication in Meckel scintigraphy.

Indexed as

Meckel scintigraphyMeckel’s diverticulumpantoprazolepreclinical imagingpremedication for Meckel scan

Identifiers

PMID38949418
PMCPMC11589266

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.