Evidence map›Paper›PMID 38948826›Full record

ArticlebioRxiv : the preprint server for biology2024

A lever hypothesis for Synaptotagmin-1 action in neurotransmitter release.

Klaudia Jaczynska, Victoria Esser, Junjie Xu, Levent Sari, Milo M Lin, Christian Rosenmund, Josep Rizo

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Klaudia JaczynskaDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Victoria EsserDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Junjie XuDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Levent SariDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Milo M LinDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Christian RosenmundCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Neurophysiology, Berlin, Germany.ORCID 0000-0002-3905-2444
Josep RizoDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.ORCID 0000-0003-1773-8311

Funding

Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
NINDS NIH HHS R35 NS097333
6 · The paper itself

Abstract

Neurotransmitter release is triggered in microseconds by Ca

Indexed as

membrane fusionmolecular dynamics simulationNeuroscienceneurotransmitter releaseSNAREssynaptic vesicle fusionsynaptotagmin

Identifiers

PMID38948826
PMCPMC11212951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.