Evidence map›Paper›PMID 38948816›Full record

ArticlebioRxiv : the preprint server for biology2024

Mutations in the albinism gene

Stefan Choy, Sunishka Thakur, Ellen Polyakov, Jennah Abdelaziz, Evan Lloyd, Maya Enriquez, Nikita Jayan, Yaouen Fily, Suzanne McGaugh, Alex C Keene and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Stefan ChoyDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Sunishka ThakurDepartment of Integrative Biology, University of Texas at Austin, Austin, TX.
Ellen PolyakovWilkes Honors College, Florida Atlantic University, Jupiter, FL.
Jennah AbdelazizDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Evan LloydFlorida State University.
Maya EnriquezDepartment of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, MN.ORCID 0000-0003-1517-3599
Nikita JayanWilkes Honors College, Florida Atlantic University, Jupiter, FL.
Yaouen FilyWilkes Honors College, Florida Atlantic University, Jupiter, FL.
Suzanne McGaughDepartment of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, MN.
Alex C KeeneDepartment of Biology, Texas A&M, College Station, TX.
Johanna E KowalkoDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.ORCID 0000-0002-3286-2954

Funding

Evolutionary approaches to identify genetic architecture regulating aggressionR35GM138345 · NIGMS · LEHIGH UNIVERSITY · PI KOWALKO, JOHANNA E. · 2020 to 2024
$2.0M
NIGMS NIH HHS R35 GM138345
6 · The paper itself

Abstract

Understanding the phenotypic consequences of naturally occurring genetic changes, as well as their impact on fitness, is fundamental to understanding how organisms adapt to an environment. This is critical when genetic variants have pleiotropic effects, as determining how each phenotype impacted by a gene contributes to fitness is essential to understand how and why traits have evolved. A striking example of a pleiotropic gene contributing to trait evolution is the

Identifiers

PMID38948816
PMCPMC11212897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.