Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Daria Amiad PavlovDepartment of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0002-8569-1597
Julie HefflerWeill Institute for Cell and Molecular Biology & Meinig School of Biomedical Engineering, Cornell University.ORCID 0000-0002-7694-0168
Carmen Suay-CorrederaDepartment of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0003-2100-4847
Mohammad DehghanyDepartment of Materials Science and Engineering, Center for Engineering Mechanobiology, University of Pennsylvania.ORCID 0009-0005-4731-5485
Kaitlyn M ShenDepartments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0002-9085-6384
Noam Zuela-SopilniakWeill Institute for Cell and Molecular Biology & Meinig School of Biomedical Engineering, Cornell University.ORCID 0000-0001-6324-1184
Rani RandellDepartment of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania.
Keita UchidaDepartment of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0001-8458-9796
Rajan JainDepartments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania.
Vivek ShenoyDepartment of Materials Science and Engineering, Center for Engineering Mechanobiology, University of Pennsylvania.ORCID 0000-0002-2645-1016
Jan LammerdingWeill Institute for Cell and Molecular Biology & Meinig School of Biomedical Engineering, Cornell University.ORCID 0000-0003-4335-8611
Benjamin ProsserDepartment of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0003-3696-9131
Funding
Nuclear mechanics and mechanotransduction in muscular laminopathiesR01HL082792 · NHLBI · CORNELL UNIVERSITY · PI LAMMERDING, JAN · 2007 to 2023
$4.8M
Detyrosinated microtubules in cardiomyocyte mechanicsR01HL133080 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Benjamin Lears Prosser · 2016 to 2026
$4.7M
Mechanical Stress-Dependent Remodeling of the Cardiac Microtubule NetworkR01HL149891 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Kenneth Ber Margulies, Benjamin Lears Prosser · 2020 to 2026
$4.2M
Defining nuclear mechanisms for ultrarapid mechanically induced gene expressionR01AR084664 · NIAMS · CORNELL UNIVERSITY · PI JOHN T LIS, Jan Lammerding · 2024 to 2026
$1.8M
Nuclear mechanobiology in confined migration (equipment supplement 2026)R35GM153257 · NIGMS · CORNELL UNIVERSITY · PI Jan Lammerding · 2024 to 2026
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Microtubule forces drive nuclear damage in · full record | OpenQuestion