Evidence map›Paper›PMID 38948412›Full record

ReviewWorld journal of experimental medicine2024

Innovation in pathogenesis and management of aortic aneurysm.

Maryam Barkhordarian, Hadrian Hoang-Vu Tran, Aiswarya Menon, Sai Priyanka Pulipaka, Izage Kianifar Aguilar, Axel Fuertes, Shraboni Dey, Angel Ann Chacko, Tanni Sethi, Ayrton Bangolo and 1 more

Abstract readReview
In one paragraph

Review in World journal of experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Association BetweenGenes · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maryam BarkhordarianDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States. marybarkhordar@gmail.com.
Hadrian Hoang-Vu TranDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Aiswarya MenonDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Sai Priyanka PulipakaDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Izage Kianifar AguilarDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Axel FuertesDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Shraboni DeyDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Angel Ann ChackoDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Tanni SethiDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Ayrton BangoloDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.
Simcha WeissmanDepartment of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic aneurysm (AA) refers to the persistent dilatation of the aorta, exceeding three centimeters. Investigating the pathophysiology of this condition is important for its prevention and management, given its responsibility for more than 25000 deaths in the United States. AAs are classified based on their location or morphology. various pathophysiologic pathways including inflammation, the immune system and atherosclerosis have been implicated in its development. Inflammatory markers such as transforming growth factor β, interleukin-1β, tumor necrosis factor-α, matrix metalloproteinase-2 and many more may contribute to this phenomenon. Several genetic disorders such as Marfan syndrome, Ehler-Danlos syndrome and Loeys-Dietz syndrome have also been associated with this disease. Recent years has seen the investigation of novel management of AA, exploring the implication of different immune suppressors, the role of radiation in shrinkage and prevention, as well as minimally invasive and newly hypothesized surgical methods. In this narrative review, we aim to present the new contributing factors involved in pathophysiology of AA. We also highlighted the novel management methods that have demonstrated promising benefits in clinical outcomes of the AA.

Indexed as

Abdominal aneurysmAortic aneurysmImmunotherapyInflammation and molecular pathwaysPathophysiologySurgical managementThoracic aneurysm

Identifiers

PMID38948412
PMCPMC11212750

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.