ArticleFrontiers in genetics2024
Transcriptome meta-analysis reveals the hair genetic rules in six animal breeds and genes associated with wool fineness.
Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- The mechanism of m6A methylation analysis of the transcriptome to regulate the diameter of Alpine Merino wool fiber.Animal bioscience · 2026Article
- Transcriptome and proteome combined analysis of wool fiber diameter regulation mechanism.Animal bioscience · 2026Article
- Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep.Frontiers in cell and developmental biology · 2026Article
- Disruptions in gene interaction networks abolish host susceptibility to Trichostrongylus colubriformis infections in sheep.PLoS neglected tropical diseases · 2025Article
- Article
- Genetic Evaluation of Early Growth Traits in Yunnan Semi-Fine Wool Sheep.Animals : an open access journal from MDPI · 2025Article
- Transcriptomic analysis revealed that oar-miR-370-3p was involved in the regulation of wool fineness in Ordos fine-wool sheep.Frontiers in veterinary science · 2025Article
- Correlation and regression analysis of KRT35 and TCHHL1 functional genes for cashmere fineness in Liaoning cashmere goats.Journal, genetic engineering & biotechnology · 2024Article
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Authors and funding
10 authors.
Funding
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Abstract
Wool plays an irreplaceable role in the lives of livestock and the textile industry. The variety of hair quality and shape leads to the diversity of its functions and applications, and the finer wool has a higher economic value. In this study, 10 coarse and 10 fine ordos fine wool sheep skin samples were collected for RNA-seq, and coarse and fine skin/hair follicle RNA-seq datasets of other five animal breeds were obtained from NCBI. Weighted gene co-expression network analysis showed that the common genes were clustered into eight modules. Similar gene expression patterns in sheep and rabbits with the same wool types, different gene expression patterns in animal species with different hair types, and brown modules were significantly correlated with species and breeds. GO and KEGG enrichment analyses showed that, most genes in the brown module associated with hair follicle development. Hence, gene expression patterns in skin tissues may determine hair morphology in animal. The analysis of differentially expressed genes revealed that 32 highly expressed candidate genes associated with the wool fineness of Ordos fine wool sheep. Among them,
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