Evidence map›Paper›PMID 38948195›Full record

ArticleJournal of inflammation research2024

Indole Lactic Acid in Plasma and Urine: A Potential Biomarker for Chronic Kidney Disease and Inflammatory.

Hao Hong, Junyao Zheng, Haimin Shi, Suya Zhou, Yue Chen, Ming Li

Abstract read
In one paragraph

Article in Journal of inflammation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hao Hong *Intensive Care Unit, the First Affiliated Hospital of Soochow University, Soochow, People's Republic of China.
Junyao Zheng *Laboratory Nephrology, the First Affiliated Hospital of Soochow University, Soochow, People's Republic of China.
Haimin ShiLaboratory Nephrology, the First Affiliated Hospital of Soochow University, Soochow, People's Republic of China.
Suya ZhouLaboratory Nephrology, Jinshan Hospital of Fudan University, Shanghai, People's Republic of China.
Yue ChenLaboratory Nephrology, the First People's Hospital of Kunshan, Soochow, People's Republic of China.
Ming LiLaboratory Nephrology, the First Affiliated Hospital of Soochow University, Soochow, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aimed to explore changes in plasma and urine indole lactic acid (ILA) levels and the relationship between inflammation and ILA in chronic kidney disease (CKD) patients and healthy people. Patients and Methods: Forty-seven CKD patients and 30 healthy individuals were included in this study. One-way ANOVA was used for variables with normal distribution and homogeneous variance. A rank-sum test was performed for non-normally distributed variables. Correlation analyses were performed using Pearson's or Spearman correlation analyses. Independent relationship between patients and CKD was analyzed using ordinal and binary logistic regressions. Receiver operating characteristic (ROC) curve was used. Results: Plasma and urine ILA levels were positively correlated (r = 0.51, Conclusion: Plasma and urine ILA can potentially be used as biomarkers of CKD and inflammatory status.

Indexed as

inflammationmetabolomicspredictortryptophan metabolism

Identifiers

PMID38948195
PMCPMC11214754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.