Evidence map›Paper›PMID 38948143›Full record

ArticlemLife2024

Phage-displayed heptapeptide sequence conjugation significantly improves the specific targeting ability of antimicrobial peptides against

Tao Wang, Peng Tan, Qi Tang, Chenlong Zhou, Yakun Ding, Shenrui Xu, Mengda Song, Huiyang Fu, Yucheng Zhang, Xiaohui Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Identification and Characterization of a Novel GAPDH-Derived Antimicrobial Peptide From Jellyfish.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tao WangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Peng TanState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Qi TangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Chenlong ZhouState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Yakun DingKey Laboratory of Innovative Utilization of Indigenous Cattle and Sheep Germplasm Resources (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs Zhengzhou University Zhengzhou China.
Shenrui XuState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Mengda SongKey Laboratory of Innovative Utilization of Indigenous Cattle and Sheep Germplasm Resources (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs Zhengzhou University Zhengzhou China.
Huiyang FuState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Yucheng ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.
Xiaohui ZhangLuoyang Key Laboratory of Animal Genetic and Breeding, College of Animal Science Henan University of Science and Technology Luoyang China.
Yueyu BaiKey Laboratory of Innovative Utilization of Indigenous Cattle and Sheep Germplasm Resources (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs Zhengzhou University Zhengzhou China.
Zhihong SunLaboratory for Bio-Feed and Molecular Nutrition, Department of Animal Science and Technology Southwest University Chongqing China.
Xi MaState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology China Agricultural University Beijing China.ORCID 0000-0003-4562-9331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Broad-spectrum antibacterial drugs often lack specificity, leading to indiscriminate bactericidal activity, which can disrupt the normal microbial balance of the host flora and cause unnecessary cytotoxicity during systemic administration. In this study, we constructed a specifically targeted antimicrobial peptide against

Indexed as

antimicrobial peptidesmembrane disruption mechanismmicrobial infectionphage display technologyStaphylococcus aureus

Identifiers

PMID38948143
PMCPMC11211671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.