Evidence map›Paper›PMID 38948141›Full record

ArticlemLife2024

Identification of 3-ketocapnine reductase activity within the human microbiota.

Xiaotong Wu, Lukuan Hou, Haili Zhang, Yi Ma, Jufang Wang, Mingwei Cai, Xiaoyu Tang

Abstract read
In one paragraph

Article in mLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaotong WuSchool of Biology and Biological Engineering South China University of Technology Guangzhou China.
Lukuan HouInstitute of Chemical Biology, Shenzhen Bay Laboratory Shenzhen China.
Haili ZhangInstitute of Chemical Biology, Shenzhen Bay Laboratory Shenzhen China.
Yi MaSchool of Biology and Biological Engineering South China University of Technology Guangzhou China.
Jufang WangSchool of Biology and Biological Engineering South China University of Technology Guangzhou China.
Mingwei CaiInstitute of Chemical Biology, Shenzhen Bay Laboratory Shenzhen China.
Xiaoyu TangInstitute of Chemical Biology, Shenzhen Bay Laboratory Shenzhen China.ORCID 0000-0002-7855-5984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbial synthesis of sulfonolipids within the human body is likely involved in maintaining human health or causing diseases. However, the enzymes responsible for their biosynthesis remain largely unknown. In this study, we identified and verified the role of 3-ketocapnine reductase, the third-step enzyme, in the four-step conversion of l-phosphoserine into sulfobacin B both in vivo and in vitro. This finding builds upon our previous research into sulfonolipid biosynthesis, which focused on the vaginal bacterium

Indexed as

3‐ketocapnine reductasecapnineshuman microbiotasulfonolipids

Identifiers

PMID38948141
PMCPMC11211663

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.