Evidence map›Paper›PMID 38947965›Full record

ArticleWorld journal of transplantation2024

Impact of payment source, referral site, and place of residence on outcomes after allogeneic transplantation in Mexico.

Andrés Gómez-De León, Yesica A López-Mora, Valeria García-Zárate, Ana Varela-Constantino, Sergio U Villegas-De Leon, Xitlaly J González-Leal, Raúl Del Toro-Mijares, Anna C Rodríguez-Zúñiga, Juan F Barrios-Ruiz, Victor Mingura-Ledezma and 6 more

Abstract read
In one paragraph

Article in World journal of transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Andrés Gómez-De LeónHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Yesica A López-MoraHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Valeria García-ZárateHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Ana Varela-ConstantinoHematology Service, Clínica Gómez Almaguer, Monterrey 64710, Nuevo León, Mexico.
Sergio U Villegas-De LeonHematology Service, Clínica Gómez Almaguer, Monterrey 64710, Nuevo León, Mexico.
Xitlaly J González-LealHematology Service, Clínica Gómez Almaguer, Monterrey 64710, Nuevo León, Mexico.
Raúl Del Toro-MijaresHematology Service, Clínica Gómez Almaguer, Monterrey 64710, Nuevo León, Mexico.
Anna C Rodríguez-ZúñigaHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Juan F Barrios-RuizHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Victor Mingura-LedezmaHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Perla R Colunga-PedrazaHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Olga G Cantú-RodríguezHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
César H Gutiérrez-AguirreHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Luz Tarín-ArzagaHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.
Elías E González-LópezHematology Service, Clínica Gómez Almaguer, Monterrey 64710, Nuevo León, Mexico.
David Gómez-AlmaguerHematology Service, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Monterrey 64460, Nuevo León, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of social determinants of health in allogeneic transplant recipients in low- and middle-income countries is poorly described. This observational study analyzes the impact of place of residence, referring institution, and transplant cost coverage (out-of-pocket

aimTo evaluate the impact of social determinants of health and their relationship with outcomes among allogeneic transplant recipients in Mexico.

methodsIn this retrospective cohort study, we included adolescents and adults ≥ 16 years who received a matched sibling or haploidentical transplant from 2015-2022. Participants were selected without regard to their diagnosis and were sourced from both a private clinic and a public University Hospital in Mexico. Three payment groups were compared: Out-of-pocket (OOP), private insurance, and a federal Universal healthcare program "Seguro Popular". Outcomes were compared between referred and institution-diagnosed patients, and between residents of Nuevo Leon and out-of-state. Primary outcomes included overall survival (OS), categorized by residence, referral, and payment source. Secondary outcomes encompassed early mortality, event-free-survival, graft-versus-host-relapse-free survival, and non-relapse-mortality (NRM). Statistical analyses employed appropriate tests, Kaplan-Meier method, and Cox proportional hazard regression modeling. Statistical software included SPSS and R with tidycmprsk library.

resultsOur primary outcome was overall survival. We included 287 patients,

conclusionIn this Latin-American multicenter study, the site of residence or referral for alloHSCT did not impact outcomes. However, access to healthcare coverage for alloHSCT was associated with improved OS and reduced NRM.

Indexed as

Aplastic anemiaFinancial toxicityGeographyHaploidenticalHealth services and outcomesHematopoietic cell transplantHematopoietic malignancyOut-of-pocketSocial determinants of healthSurvival

Identifiers

PMID38947965
PMCPMC11212586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.