Evidence map›Paper›PMID 38947523›Full record

ArticleiScience2024

Metaproteomics reveals parallel utilization of colonic mucin glycans and dietary fibers by the human gut microbiota.

Grete Raba, Ana S Luis, Hannah Schneider, Indrek Morell, Chunsheng Jin, Signe Adamberg, Gunnar C Hansson, Kaarel Adamberg, Liisa Arike

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Biology ofAnnual review of microbiology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Grete RabaDepartment of Chemistry and Biotechnology, Tallinn University of Technology, 12618 Tallinn, Estonia.
Ana S LuisDepartment of Medical Biochemistry and Cell Biology, University of Gothenburg, 41390 Gothenburg, Sweden.
Hannah SchneiderDepartment of Medical Biochemistry and Cell Biology, University of Gothenburg, 41390 Gothenburg, Sweden.
Indrek MorellCenter of Food and Fermentation Technologies, 12618 Tallinn, Estonia.
Chunsheng JinDepartment of Medical Biochemistry and Cell Biology, University of Gothenburg, 41390 Gothenburg, Sweden.
Signe AdambergDepartment of Chemistry and Biotechnology, Tallinn University of Technology, 12618 Tallinn, Estonia.
Gunnar C HanssonDepartment of Medical Biochemistry and Cell Biology, University of Gothenburg, 41390 Gothenburg, Sweden.
Kaarel AdambergDepartment of Chemistry and Biotechnology, Tallinn University of Technology, 12618 Tallinn, Estonia.
Liisa ArikeDepartment of Medical Biochemistry and Cell Biology, University of Gothenburg, 41390 Gothenburg, Sweden.

Funding

Unraveling the enzymatic pathway of gut bacterial mucus degradation to treat inflammationR01DK125445 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOROPATKIN, NICOLE M, MARTENS, ERIC C · 2020 to 2023
$2.2M
NIDDK NIH HHS R01 DK125445
6 · The paper itself

Abstract

A diet lacking dietary fibers promotes the expansion of gut microbiota members that can degrade host glycans, such as those on mucins. The microbial foraging on mucin has been associated with disruptions of the gut-protective mucus layer and colonic inflammation. Yet, it remains unclear how the co-utilization of mucin and dietary fibers affects the microbiota composition and metabolic activity. Here, we used 14 dietary fibers and porcine colonic and gastric mucins to study the dynamics of mucin and dietary fiber utilization by the human fecal microbiota

Indexed as

Microbiomeomics

Identifiers

PMID38947523
PMCPMC11214529

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.