Evidence map›Paper›PMID 38946943›Full record

ArticleResearch square2024

The role of Tyr34 in proton-coupled electron transfer of human manganese superoxide dismutase.

Gloria Borgstahl, Jahaun Azadmanesh, Katelyn Slobodnik, Lucas Struble, Erika Cone, Medhanjali Dasgupta, William Lutz, Siddhartha Kumar, Amarnath Natarajan, Leighton Coates and 3 more

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Gloria BorgstahlUniversity of Nebraska Medical Center.ORCID 0000-0001-8070-0258
Jahaun AzadmaneshUniversity of Nebraska Medical Center.ORCID 0000-0002-3615-7785
Katelyn SlobodnikUniversity of Nebraska Medical Center.ORCID 0009-0004-0951-5315
Lucas StrubleUniversity of Nebraska Medical Center.
Erika ConeUniversity of Nebraska Medical Center.
Medhanjali DasguptaUniversity of Nebraska Medical Center.ORCID 0000-0003-2509-3699
William LutzUniversity of Nebraska Medical Center.
Siddhartha KumarUniversity of Nebraska Medical Center.
Amarnath NatarajanUniversity of Nebraska Medical Center.ORCID 0000-0001-5067-0203
Leighton CoatesOak Ridge National Laboratory.ORCID 0000-0003-2342-049X
Kevin WeissOak Ridge National Laboratory.ORCID 0000-0002-6486-8007
Dean MylesOak Ridge National Laboratory.ORCID 0000-0002-7693-4964
Thomas KrollStanford Synchrotron Radiation Lightsource.

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI James Eudy · 1985 to 2026
$55.0M
A Synchrotron Radiation Structural Biology ResourcesP30GM133894 · NIGMS · STANFORD UNIVERSITY · PI Aina E. Cohen, KEITH O HODGSON · 2020 to 2026
$43.3M
Deciphering the Enzymatic Mechanism of Superoxide DismutaseR01GM145647 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Gloria Borgstahl · 2022 to 2026
$2.3M
NCI NIH HHS P30 CA036727NIGMS NIH HHS P30 GM133894NIGMS NIH HHS R01 GM145647
6 · The paper itself

Abstract

Human manganese superoxide dismutase (MnSOD) plays a crucial role in controlling levels of reactive oxygen species (ROS) by converting superoxide (O

Identifiers

PMID38946943
PMCPMC11213228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.