Evidence map›Paper›PMID 38946902›Full record

ArticleFrontiers in microbiology2024

Genetics of resistance to trimethoprim in cotrimoxazole resistant uropathogenic

María Eloísa Poey, Eliana de Los Santos, Diego Aznarez, César X García-Laviña, Magela Laviña

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. UropathogenicAntibiotics (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Mutation analysis of dihydrofolate reductase (Iranian journal of microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Temporal Trends ofAntibiotics (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

María Eloísa PoeySección Fisiología & Genética Bacterianas, Facultad de Ciencias, Montevideo, Uruguay.
Eliana de Los SantosSección Fisiología & Genética Bacterianas, Facultad de Ciencias, Montevideo, Uruguay.
Diego AznarezSección Fisiología & Genética Bacterianas, Facultad de Ciencias, Montevideo, Uruguay.
César X García-LaviñaSección Bioquímica, Facultad de Ciencias, Montevideo, Uruguay.
Magela LaviñaSección Fisiología & Genética Bacterianas, Facultad de Ciencias, Montevideo, Uruguay.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cotrimoxazole, the combined formulation of sulfamethoxazole and trimethoprim, is one of the treatments of choice for several infectious diseases, particularly urinary tract infections. Both components of cotrimoxazole are synthetic antimicrobial drugs, and their combination was introduced into medical therapeutics about half a century ago. In Gram-negative bacteria, resistance to cotrimoxazole is widespread, being based on the acquisition of genes from the auxiliary genome that confer resistance to each of its antibacterial components. Starting from previous knowledge on the genotype of resistance to sulfamethoxazole in a collection of cotrimoxazole resistant uropathogenic

Indexed as

antibiotic resistancecotrimoxazoleEscherichia coligene cassettesintegronsplasmid transfertransposonstrimethoprim

Identifiers

PMID38946902
PMCPMC11213556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.