Evidence map›Paper›PMID 38946778›Full record

ArticleHealth science reports2024

The pressing need for study on the effects of Mpox on the progression of vascular inflammation: A well-timed call.

Sara Shahid Meem, Amrin Yeasin Proma, Mohiuddin Ahmed Bhuiyan, Syed Masudur Rahman Dewan

Abstract read
In one paragraph

Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara Shahid MeemDepartment of Pharmacy, School of Medicine University of Asia Pacific Dhaka Bangladesh.ORCID https://orcid.org/0009-0001-1667-2931
Amrin Yeasin PromaDepartment of Pharmacy, School of Medicine University of Asia Pacific Dhaka Bangladesh.ORCID https://orcid.org/0009-0006-1357-6027
Mohiuddin Ahmed BhuiyanDepartment of Pharmacy, School of Medicine University of Asia Pacific Dhaka Bangladesh.ORCID https://orcid.org/0000-0002-2218-4061
Syed Masudur Rahman DewanDepartment of Pharmacy, School of Medicine University of Asia Pacific Dhaka Bangladesh.ORCID https://orcid.org/0000-0003-1443-7150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This article explored the possibility that the Mpox virus (MPXV) may initiate or stimulate the consequences of vascular inflammation. In 1970, it was discovered that Macaca cynomolgus primates infected with MPXV also infected humans in the Democratic Republic of the Congo. Discussion: The study demonstrates that MPXV invades host cells via viral proteins and surface receptors, initiating the release of diverse inflammatory mediators such as IL-1, IL-6, TNF-α, CCL2, CXCL2, CXCL8, CXCL10, and so forth probably through endothelial dysfunction by reactive oxygen species production. In general, these mediators have been found to contribute to vascular inflammation and the formation of atherosclerotic plaque at a later stage, which may contribute to the onset of vascular inflammation. Conclusion: The discussed association between vascular inflammation and Mpox has the potential to be an important finding in the field of vascular biology research.

Indexed as

atherosclerosiscardiovascular diseasesendothelial dysfunctionMpoxoxidative stressvascular inflammation

Identifiers

PMID38946778
PMCPMC11211998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.