Evidence map›Paper›PMID 38946719›Full record

ArticleJournal of cell communication and signaling2024

Adipocyte enhancer binding protein 1 knockdown alleviates osteoarthritis through inhibiting NF-κB signaling pathway-mediated inflammation and extracellular matrix degradation.

Le Cao, Weilu Gao, Haitao Yang, Ran Zeng, Zongsheng Yin

Abstract read
In one paragraph

Article in Journal of cell communication and signaling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Identification of shared key genes and pathways in osteoarthritis and sarcopenia patients based on bioinformatics analysis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Le CaoDepartment of Orthopedics The First Affiliated Hospital of Anhui Medical University Hefei Anhui China.ORCID https://orcid.org/0000-0002-7466-1237
Weilu GaoDepartment of Orthopedics The First Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Haitao YangDepartment of Orthopedics Fuyang Hospital of Anhui Medical University Fuyang Anhui China.
Ran ZengDepartment of Intensive Care Unit Fuyang Hospital of Anhui Medical University Fuyang Anhui China.
Zongsheng YinDepartment of Orthopedics The First Affiliated Hospital of Anhui Medical University Hefei Anhui China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation promotes the degradation of the extracellular matrix, which contributes to the development of osteoarthritis (OA). Adipocyte enhancer binding protein 1 (AEBP1) participates in multiple pathological processes related to inflammatory diseases. However, the role of AEBP1 in OA development is unknown. We found a higher AEBP1 expression in articular cartilage of OA patients (

Indexed as

adipocyte enhancer binding protein 1extracellular matrixinflammationosteoarthritis

Identifiers

PMID38946719
PMCPMC11208125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.