Evidence map›Paper›PMID 38946491›Full record

ArticleJournal of materials chemistry. B2024

Cationic-motif-modified exosomes for mRNA delivery to retinal photoreceptors.

Héctor A Millán Cotto, Tanvi Vinod Pathrikar, Bill Hakim, Helna M Baby, Hengli Zhang, Peng Zhao, Ronak Ansaripour, Rouzbeh Amini, Rebecca L Carrier, Ambika G Bajpayee

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  5. Exosomes in corneal diseases: advances in diagnosis and therapy.Frontiers in cell and developmental biology · 2026
    Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Héctor A Millán CottoDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.ORCID http://orcid.org/0009-0009-5072-908X
Tanvi Vinod PathrikarDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.
Bill HakimDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.
Helna M BabyDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.
Hengli ZhangDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.
Peng ZhaoDepartment of Chemical Engineering, Northeastern University, Boston, MA 02115, USA. pe.zhao@northeastern.edu.
Ronak AnsaripourDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.
Rouzbeh AminiDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.ORCID http://orcid.org/0000-0003-3632-6195
Rebecca L CarrierDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.
Ambika G BajpayeeDepartment of Bioengineering, Northeastern University, Boston, MA, 02115, USA. millancotto.h@northeastern.edu.ORCID http://orcid.org/0000-0002-8458-7464

Funding

Anti-catabolic drug anchored cationic exosomes for cartilage targeting and repairR21EB028385 · NIBIB · NORTHEASTERN UNIVERSITY · PI BAJPAYEE, AMBIKA GOEL · 2019 to 2021
$628k
NIBIB NIH HHS R21 EB028385
6 · The paper itself

Abstract

Topical treatment of vitreoretinal diseases remains a challenge due to slow corneal uptake and systemic clearance. Exosomes are emerging nanocarriers for drug delivery due to biocompatibility and cellular targeting properties. To apply them for retinal targeting

Indexed as

ExosomesRNA, MessengerAnimalsCationsCattlePhotoreceptor Cells, VertebrateCationsRNA, Messenger

Identifiers

PMID38946491
PMCPMC11323772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.