Evidence map›Paper›PMID 38946424›Full record

ArticleActa biochimica et biophysica Sinica2024

miR-373-3p promotes aerobic glycolysis in colon cancer cells by targeting MFN2.

Yu Wang, Jie Lun, Yuying Zhang, Mengchao Yu, Xingqian Liu, Jing Guo, Hongwei Zhang, Wensheng Qiu, Jing Fang

Abstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu WangDepartment of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao 266071, China.
Jie LunDepartment of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao 266071, China.
Yuying ZhangSchool of Public Health, Qingdao University, Qingdao 266071, China.
Mengchao YuCentral Laboratory, Qingdao Municipal Hospital, Qingdao 266071, China.
Xingqian LiuDepartment of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao 266071, China.
Jing GuoDepartment of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao 266071, China.
Hongwei ZhangShandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan 250014, China.
Wensheng QiuDepartment of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao 266071, China.
Jing FangDepartment of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao 266071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are implicated in the development of cancers and may serve as potential targets for therapy. However, the functions and underlying mechanisms of miRNAs in cancers are not well understood. This work aims to study the role of miR-373-3p in colon cancer cells. We find that the expression of miR-373-3p mimics promotes and the miR-373-3p inhibitor suppresses aerobic glycolysis and proliferation of colon cancer cells. Mechanistically, miR-373-3p inhibits the expression of

Indexed as

Colonic NeoplasmsGlycolysisGTP PhosphohydrolasesMicroRNAsMitochondrial ProteinsAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMiceMice, Inbred BALB CMice, NudeGTP PhosphohydrolasesMFN2 protein, humanMicroRNAsMIRN373 microRNA, humanMitochondrial Proteinscell proliferationcolon cancerglycolysisMFN2miR-373-3pmiRNA

Identifiers

PMID38946424
PMCPMC11612643

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.