Evidence map›Paper›PMID 38946073›Full record

ArticleRadiation oncology journal2024

The role of histology on the outcome of sinonasal carcinomas treated with radiotherapy: a single institution experience.

Ali Kazemian, Borna Farazmand, Maryam Taherioun, Mahdie Razmkhah, Mohammad Shirkhoda, Amirmohsen Jalaeefar, Ata Garajei, Mehrdad Jafari, Farrokh Heidari, Mahdi Aghili and 1 more

Abstract read
In one paragraph

Article in Radiation oncology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ali KazemianDepartment of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Borna FarazmandRadiation Oncology Research Center, Cancer Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Maryam TaheriounDepartment of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mahdie RazmkhahDepartment of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad ShirkhodaDepartment of Oncosurgery, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Amirmohsen JalaeefarDepartment of Oncosurgery, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Ata GarajeiDepartment of Head and Neck Surgical Oncology and Reconstructive Surgery, Cancer Institute, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mehrdad JafariDepartment of Oto-Rhino-Laryngology and Head and Neck Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Farrokh HeidariDepartment of Oto-Rhino-Laryngology and Head and Neck Surgery, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mahdi AghiliRadiation Oncology Research Center, Cancer Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Reza GhalehtakiRadiation Oncology Research Center, Cancer Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Funding

Tehran University of Medical Sciences 99-1-248-47949
6 · The paper itself

Abstract

purposeSinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy. MATERIALS AND

methodsIn this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type.

resultsA total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively.

conclusionDifferent histopathologies of sinonasal cancer seem to have different patterns of failure, and this may be considered in the treatment approach.

Indexed as

Adenoid cystic carcinomaHead and neck neoplasmsParanasal sinus neoplasmsRadiotherapySquamous cell carcinomaTreatment outcome

Identifiers

PMID38946073
PMCPMC11215502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.