Evidence map›Paper›PMID 38946059›Full record

ArticlePhysiological reports2024

Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HT

Ronald J Trotta, David L Harmon, James L Klotz

Abstract read
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ronald J TrottaDepartment of Animal and Food Sciences, University of Kentucky, Lexington, Kentucky, USA.
David L HarmonDepartment of Animal and Food Sciences, University of Kentucky, Lexington, Kentucky, USA.
James L KlotzForage-Animal Production Research Unit, USDA-ARS, Lexington, Kentucky, USA.ORCID 0000-0001-9728-1889

Funding

USDA-ARS, Forage-Animal Production Research Unit and Kentucky Agricultural Experiment Station 58-5042-3-004-001SUSDA-ARS, National Program 101 5042-32630-004-000-D
6 · The paper itself

Abstract

To better understand mechanisms of serotonin- (5-HT) mediated vasorelaxation, isolated lateral saphenous veins from cattle were assessed for vasoactivity using myography in response to increasing concentrations of 5-HT or selective 5-HT receptor agonists. Vessels were pre-contracted with 1 × 10

Indexed as

Saphenous VeinSerotoninVasodilationAnimalsCattleMalePhenylephrineReceptors, SerotoninReceptors, Serotonin, 5-HT4Serotonin Receptor AgonistsPhenylephrineReceptors, SerotoninReceptors, Serotonin, 5-HT4SerotoninSerotonin Receptor Agonists5‐hydroxytryptamineBIMU 8cattleG protein‐coupled receptorruminant

Identifiers

PMID38946059
PMCPMC11214916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.