Evidence map›Paper›PMID 38945974›Full record

ArticleNature ecology & evolution2024

Extant and extinct bilby genomes combined with Indigenous knowledge improve conservation of a unique Australian marsupial.

Carolyn J Hogg, Richard J Edwards, Katherine A Farquharson, Luke W Silver, Parice Brandies, Emma Peel, Merly Escalona, Frederick R Jaya, Rujiporn Thavornkanlapachai, Kimberley Batley and 24 more

Erratum issuedAbstract read
In one paragraph

Article in Nature ecology & evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Loss-of-function mutations inBiology letters · 2025
    Article
  5. Article
  6. Looking back on 2024.Nature ecology & evolution · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Carolyn J Hogg *School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia. carolyn.hogg@sydney.edu.au.ORCID http://orcid.org/0000-0002-6328-398X
Richard J Edwards *Minderoo OceanOmics Centre at UWA, Oceans Institute, The University of Western Australia, Perth, Western Australia, Australia.ORCID http://orcid.org/0000-0002-3645-5539
Katherine A Farquharson *School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-9009-7453
Luke W SilverSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Parice BrandiesSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Emma PeelSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Merly EscalonaDepartment of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, CA, USA.ORCID http://orcid.org/0000-0003-0213-4777
Frederick R JayaSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Rujiporn ThavornkanlapachaiBiodiversity and Conservation Science, Department of Biodiversity, Conservation and Attractions, Kensington, Western Australia, Australia.
Kimberley BatleySchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Tessa M BradfordEvolutionary Biology Unit, South Australian Museum, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0003-0607-1398
J King ChangSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0009-0007-8748-4368
Zhiliang ChenIllumina, Melbourne, Victoria, Australia.
Nandan DeshpandeSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, New South Wales, Australia.
Martin DziminskiBiodiversity and Conservation Science, Department of Biodiversity, Conservation and Attractions, Kensington, Western Australia, Australia.
Kyle M EwartSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Oliver W GriffithSchool of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0001-9703-7800
Laia Marin GualDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.ORCID http://orcid.org/0000-0003-1480-0976
Katherine L MoonDepartment of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, CA, USA.
Kenny J TravouillonCollections and Research, Western Australian Museum, Welshpool, Western Australia, Australia.
Paul WatersSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-4689-8747
Camilla M WhittingtonSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0001-5765-9699
Marc R WilkinsSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, New South Wales, Australia.
Kristofer M HelgenAustralian Museum Research Institute, Australian Museum, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-8776-4040
Nathan LoSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-2176-2840
Simon Y W HoSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-0361-2307
Aurora Ruiz HerreraDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.ORCID http://orcid.org/0000-0003-3868-6151
Rachel PaltridgeIndigenous Desert Alliance, Alice Springs, Northern Territory, Australia.
Jennifer A Marshall GravesDepartment of Environment and Genetics, La Trobe University, Melbourne, Victoria, Australia.
Marilyn RenfreeSchool of BioSciences, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-4589-0436
Beth ShapiroDepartment of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, CA, USA.
Kym OttewellBiodiversity and Conservation Science, Department of Biodiversity, Conservation and Attractions, Kensington, Western Australia, Australia.ORCID http://orcid.org/0000-0002-4273-3224
Kiwirrkurra Rangers
Katherine BelovSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.

Funding

Department of Education and Training | Australian Research Council (ARC) CE200100012Department of Education and Training | Australian Research Council (ARC) DP180100931Department of Education and Training | Australian Research Council (ARC) DP180102465Department of Education and Training | Australian Research Council (ARC) DP180103370Department of Education and Training | Australian Research Council (ARC) DP210103512Department of Education and Training | Australian Research Council (ARC) DP220101429Department of Education and Training | Australian Research Council (ARC) FT160100167Department of Education and Training | Australian Research Council (ARC) LP18010072Department of Health | National Health and Medical Research Council (NHMRC) 2021172
6 · The paper itself

Abstract

Ninu (greater bilby, Macrotis lagotis) are desert-dwelling, culturally and ecologically important marsupials. In collaboration with Indigenous rangers and conservation managers, we generated the Ninu chromosome-level genome assembly (3.66 Gbp) and genome sequences for the extinct Yallara (lesser bilby, Macrotis leucura). We developed and tested a scat single-nucleotide polymorphism panel to inform current and future conservation actions, undertake ecological assessments and improve our understanding of Ninu genetic diversity in managed and wild populations. We also assessed the beneficial impact of translocations in the metapopulation (N = 363 Ninu). Resequenced genomes (temperate Ninu, 6; semi-arid Ninu, 6; and Yallara, 4) revealed two major population crashes during global cooling events for both species and differences in Ninu genes involved in anatomical and metabolic pathways. Despite their 45-year captive history, Ninu have fewer long runs of homozygosity than other larger mammals, which may be attributable to their boom-bust life history. Here we investigated the unique Ninu biology using 12 tissue transcriptomes revealing expression of all 115 conserved eutherian chorioallantoic placentation genes in the uterus, an XY

Indexed as

Conservation of Natural ResourcesGenomeMarsupialiaAnimalsAustraliaExtinction, BiologicalPolymorphism, Single Nucleotide

Identifiers

PMID38945974
PMCPMC11239497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.