Evidence map›Paper›PMID 38945956›Full record

ArticleExperimental & molecular medicine2024

Phospholipase C-β3 is dispensable for vascular constriction but indispensable for vascular hyperplasia.

Seo Yeon Jin, Jung Min Ha, Hye Jin Kum, Ji Soo Ma, Hong Koo Ha, Sang Heon Song, Yong Ryoul Yang, Ho Lee, Yoon Soo Bae, Masahiro Yamamoto and 2 more

Abstract read
In one paragraph

Article in Experimental & molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Seo Yeon JinMedical Research Institute, Department of Pharmacology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Jung Min HaMedical Research Institute, Department of Pharmacology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Hye Jin KumMedical Research Institute, Department of Pharmacology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Ji Soo MaDepartment of Immunoparasitology, Osaka University, Suita, Japan.
Hong Koo HaDepartment of Urology, Pusan National University Hospital, Busan, Republic of Korea.
Sang Heon SongDepartment of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Yong Ryoul YangAging Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
Ho LeeCarcinogenesis and Metastasis Research Branch, National Cancer Center, Goyang, Republic of Korea.ORCID http://orcid.org/0000-0001-5573-742X
Yoon Soo BaeDepartment of Life Science, Ewha Womans University, Seoul, Republic of Korea.
Masahiro YamamotoDepartment of Immunoparasitology, Osaka University, Suita, Japan.ORCID http://orcid.org/0000-0002-6821-2785
Pann-Ghill SuhKorea Brain Research Institute, Daegu, Republic of Korea.
Sun Sik BaeMedical Research Institute, Department of Pharmacology, Pusan National University School of Medicine, Yangsan, Republic of Korea. sunsik@pusan.ac.kr.ORCID http://orcid.org/0000-0002-1027-6639

Funding

National Research Foundation of Korea (NRF) 2017R1D1A1B03034515National Research Foundation of Korea (NRF) 2020R1A2C2008870National Research Foundation of Korea (NRF) RS-2023-00208788
6 · The paper itself

Abstract

Angiotensin II (AngII) induces the contraction and proliferation of vascular smooth muscle cells (VSMCs). AngII activates phospholipase C-β (PLC-β), thereby inducing Ca

Indexed as

Angiotensin IIHyperplasiaMuscle, Smooth, VascularPhospholipase C betaReactive Oxygen SpeciesVasoconstrictionAnimalsCell ProliferationMaleMiceMice, KnockoutMyocytes, Smooth Musclerho-Associated KinasesAngiotensin IIPhospholipase C betaPlcb3 protein, mouseReactive Oxygen Speciesrho-Associated Kinases

Identifiers

PMID38945956
PMCPMC11297146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.