Evidence map›Paper›PMID 38945068›Full record

ArticleClinical biomechanics (Bristol, Avon)2024

Prolonged quadriceps latency during gait early after anterior cruciate ligament injury predicts radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction.

Naoaki Ito, Jacob J Capin, Elanna K Arhos, Elizabeth Wellsandt, Ryan T Pohlig, Thomas S Buchanan, Lynn Snyder-Mackler

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In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Naoaki ItoBiomechanics and Movement Science Program, University of Delaware, Newark, DE, USA; Department of Physical Therapy, University of Delaware, Newark, DE, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin - Madison, Madison, WI, USA; Badger Athletic Performance Program, University of Wisconsin - Madison, Madison, WI, USA. Electronic address: ito@ortho.wisc.edu.
Jacob J CapinDepartment of Physical Therapy, Marquette University, Milwaukee, WI, USA; Medical College of Wisconsin, Clinical and Translational Science Institute, Milwaukee, WI, USA.
Elanna K ArhosDivision of Physical Therapy, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH, USA.
Elizabeth WellsandtPhysical Therapy Program, Department of Health and Rehabilitation Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Ryan T PohligBiostatistic Core Facility, College of Health Sciences, University of Delaware, Newark, DE, USA.
Thomas S BuchananBiomechanics and Movement Science Program, University of Delaware, Newark, DE, USA; Department of Biomedical Engineering, University of Delaware, Newark, DE, USA; Department of Mechanical Engineering, University of Delaware, Newark, DE, USA.
Lynn Snyder-MacklerBiomechanics and Movement Science Program, University of Delaware, Newark, DE, USA; Department of Physical Therapy, University of Delaware, Newark, DE, USA.

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI RIZZO, MATTHEW · 2016 to 2025
$42.8M
Dynamic Stability in the ACL Injured KneeR37HD037985 · NICHD · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2012 to 2021
$4.2M
CAN NEUROMUSCULAR TRAINING ALTER MOVEMENT PATTERNS?R01AR048212 · NIAMS · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2005 to 2015
$3.6M
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor HealthDP5OD031833 · OD · MARQUETTE UNIVERSITY · PI CAPIN, JACOB J · 2021 to 2025
$1.9M
ACL Reconstructed Knee: qMRI and Biomechanical ModelingR01HD087459 · NICHD · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2016 to 2020
$1.8M
Can we modify gait asymmetry after ACL reconstruction?F31AR078580 · NIAMS · UNIVERSITY OF DELAWARE · PI ARHOS, ELANNA · 2021 to 2022
$68k
NIAMS NIH HHS F31 AR078580NIAMS NIH HHS R01 AR048212NICHD NIH HHS R01 HD087459NICHD NIH HHS R37 HD037985NIGMS NIH HHS U54 GM115458NIH HHS DP5 OD031833
6 · The paper itself

Abstract

backgroundThe purpose was to explore quadriceps electromechanical function (quadriceps latency) during gait after anterior cruciate ligament injury as a predictor for radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Change in latency after preoperative physical therapy was also examined.

methodsQuadriceps latency (time between peak knee moment and quadriceps electromyography) was calculated before preoperative physical therapy (2.4 [0.5-7.5] months after anterior cruciate ligament injury) and after preoperative physical therapy in 24 athletes. Participants were dichotomized into osteoarthritis (Kellgren and Lawrence grade ≥ 2) and non-osteoarthritis groups at 6-years. Forward selection logistic regression was performed using z-score normalized quadriceps latency and demographics. A 2 × 2 repeated measure ANOVA was performed for quadriceps latency between groups before and after preoperative physical therapy.

findingsQuadriceps latency before preoperative physical therapy was the only predictor of 6-year radiographic osteoarthritis (p = 0.014, odds ratio [95% confidence interval] = 5.859 [1.435-23.924]). Time by group interaction was observed for quadriceps latency (p = 0.039, η

interpretationProlonged latency after anterior cruciate ligament injury may predict post-traumatic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Latency may shorten with preoperative physical therapy, yet athletes still moved on to develop osteoarthritis. Quadriceps function may need intervention immediately following anterior cruciate ligament injury for prevention of post-traumatic knee osteoarthritis.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionGaitOsteoarthritis, KneeQuadriceps MuscleAdultElectromyographyFemaleHumansKnee JointMaleRadiographyGait biomechanicsNeuromuscular controlPost-traumatic knee osteoarthritisQuadriceps

Identifiers

PMID38945068
PMCPMC11250627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.