ArticleBMC pulmonary medicine2024
Echocardiographic assessment for cardiopulmonary function in patients with congenital heart disease-related pulmonary arterial hypertension.
Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Right ventricular function, exercise capacity and quality of life in adults with congenital heart disease and the effect of a home-based exercise program.International journal of cardiology. Congenital heart disease · 2026Article
- Prevalence and Prognostic Value of Right Ventricular-Pulmonary Artery Uncoupling in Adults with Right-Sided Congenital Heart Disease.Journal of personalized medicine · 2026Article
- [Role of echocardiography in the assessment of right ventricular function in pulmonary hypertension].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Review
- A pulmonary hypertension targeted algorithm to improve referral to right heart catheterization: A machine learning approach.Computational and structural biotechnology journal · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundFor patients with congenital heart disease-related pulmonary arterial hypertension (CHD-PAH), cardiopulmonary exercise testing (CPET) can reflect cardiopulmonary reserve function. However, CPET may not be readily accessible for patients with high-risk conditions or limited mobility due to disability. Echocardiography, on the other hand, serves as a widely available diagnostic tool for all CHD-PAH patients. This study was aimed to identify the parameters of echocardiography that could serve as indicators of cardiopulmonary function and exercise capacity.
methodsA cohort of 70 patients contributed a total of 110 paired echocardiogram and CPET results to this study, with 1 year interval for repeated examinations. Echocardiography and exercise testing were conducted following standardized procedures, and the data were collected together with clinically relevant indicators for subsequent statistical analysis. Demographic comparisons were performed using t-tests and chi-square tests. Univariate and multivariate analyses were conducted to identify potential predictors of peak oxygen uptake (peak VO
resultsThe ratio of tricuspid annular plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP) was found to be the only independent indicator significantly associated with both peak VO
conclusionsTAPSE/PASP may be a feasible echocardiographic indicator for evaluating exercise tolerance.
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