Evidence map›Paper›PMID 38944658›Full record

ArticleNature communications2024

CD4

Hyun Jae Lee, Marcela L Moreira, Shihan Li, Takahiro Asatsuma, Cameron G Williams, Oliver P Skinner, Saba Asad, Michael Bramhall, Zhe Jiang, Zihan Liu and 10 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The LEF1-LAG3 axis regulates CD4Parasites & vectors · 2026
    Article
  4. T follicular helper cell development during malaria.Current opinion in immunology · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Hyun Jae Lee *Department of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Marcela L Moreira *Department of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID 0000-0003-3477-0727
Shihan LiDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Takahiro AsatsumaDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Cameron G WilliamsDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Oliver P SkinnerDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Saba AsadDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Michael BramhallDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID 0000-0001-5938-158X
Zhe JiangDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Zihan LiuDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID 0009-0007-2596-7954
Ashlyn S KerrDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID 0009-0001-9217-6497
Jessica A EngelQIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia.
Megan S F SoonQIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia.
Jasmin StraubeQIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia.ORCID 0000-0002-1748-0659
Irving BarreraBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Evan MurrayBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Fei ChenBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0003-2308-3649
Jason NidefferDepartment of Medicine, Stanford University, CA, USA.
Prasanna JagannathanDepartment of Medicine, Stanford University, CA, USA.ORCID 0000-0001-6305-758X
Ashraful HaqueDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia. Ashraful.haque@unimelb.edu.au.ORCID 0000-0003-2260-0026

Funding

Systems biological assessment of vaccination-induced protective immunity in African childrenU01AI165527 · NIAID · STANFORD UNIVERSITY · PI James Beeson, BALI PULENDRAN · 2022 to 2026
$4.0M
Stanford ChEM-H Chemistry/Biology Interface Predoctoral Training ProgramT32GM139791 · NIGMS · STANFORD UNIVERSITY · PI Carolyn Bertozzi, Christine Jacobs-Wagner · 2021 to 2026
$2.4M
Deciphering mechanisms of CD4+ T cell-dependent clinical immunity to repeated Plasmodium infectionsR01AI177377 · NIAID · STANFORD UNIVERSITY · PI Ashraful Haque, Prasanna Jagannathan · 2024 to 2026
$2.0M
Department of Health | National Health and Medical Research Council (NHMRC) 1180951NIAID NIH HHS R01 AI177377NIAID NIH HHS U01 AI165527NIGMS NIH HHS T32 GM139791
6 · The paper itself

Abstract

Children in malaria-endemic regions can experience repeated Plasmodium infections over short periods of time. Effects of re-infection on multiple co-existing CD4

Indexed as

CD4-Positive T-LymphocytesMalariaReinfectionAnimalsFemaleImmunologic MemoryMiceMice, Inbred C57BLMice, TransgenicReceptors, Antigen, T-CellSpleenTh1 CellsReceptors, Antigen, T-Cell

Identifiers

PMID38944658
PMCPMC11214622

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.