Evidence map›Paper›PMID 38944413›Full record

ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2024

Acute kidney injury in acute heart failure-when to worry and when not to worry?

Debasish Banerjee, Mahrukh Ayesha Ali, Angela Yee-Moon Wang, Vivekanand Jha

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
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  3. Risk of Hospital Readmission among People with CKD: A Population-Based Cohort Study.Clinical journal of the American Society of Nephrology : CJASN · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Debasish BanerjeeRenal and Transplantation Unit, St George's University Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0002-6863-2325
Mahrukh Ayesha AliRenal and Transplantation Unit, St George's University Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0002-4633-452X
Angela Yee-Moon WangDuke-National University of Singapore, Academic Medical Center, Singapore General Hospital, Singapore.ORCID 0000-0003-2508-7117
Vivekanand JhaFaculty of Medicine, School of Public Health, Imperial College London, London, UK.

Funding

NIHR 207236
6 · The paper itself

Abstract

Acute kidney injury is common in patients with acute decompensated heart failure. It is more common in patients with acute heart failure who suffer from chronic kidney disease. Worsening renal function is often defined as a rise in serum creatinine of more than 0.3 mg/dL (26.5 µmol/L) which, by definition, is acute kidney injury (AKI) stage 1. Perhaps the term AKI is more appropriate than worsening renal function as it is used universally by nephrologists, internists and other medical practitioners. In health, the heart and the kidney support each other to maintain the body's homeostasis. In disease, the heart and the kidney can adversely affect each other's function, causing further clinical deterioration. In patients presenting with acute heart failure and fluid overload, therapy with diuretics for decongestion often causes a rise in serum creatinine and AKI. However, in the longer term the decongestion improves survival and prevents hospital admissions despite rising serum creatinine and AKI. It is important to realize that renal venous congestion due to increased right-sided heart pressures in acute heart failure is a major cause of kidney dysfunction and hence decongestion therapy improves kidney function in the longer term. This review provides a perspective on the acceptable AKI with decongestion therapy, which is associated with improved survival, as opposed to AKI due to tubular injury related to sepsis or nephrotoxic drugs, which is associated with poor survival.

Indexed as

Acute Kidney InjuryHeart FailureAcute DiseaseDiureticsHumansPrognosisDiureticsacute heart failureacute kidney injurydecongestiondiuretic therapyfluid overload

Identifiers

PMID38944413
PMCPMC11879425

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.