Evidence map›Paper›PMID 38943617›Full record

ArticleJournal of proteome research2024

Ex-Vivo

Daniel Radford-Smith, Tang T Ng, Abi G Yates, Isobel Dunstan, Timothy D W Claridge, Daniel C Anthony, Fay Probert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Lesion level and severity acutely influence metabolomic profiles in spinal cord injury.Journal of neuropathology and experimental neurology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel Radford-SmithDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.
Tang T NgDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.
Abi G YatesDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.
Isobel DunstanPharmacology Department, University of Oxford, Oxford OX1 3QT, U.K.
Timothy D W ClaridgeDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.
Daniel C AnthonyPharmacology Department, University of Oxford, Oxford OX1 3QT, U.K.
Fay ProbertDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.ORCID 0000-0002-8580-2023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor (TNF) has well-established roles in neuroinflammatory disorders, but the effect of TNF on the biochemistry of brain cells remains poorly understood. Here, we microinjected TNF into the brain to study its impact on glial and neuronal metabolism (glycolysis, pentose phosphate pathway, citric acid cycle, pyruvate dehydrogenase, and pyruvate carboxylase pathways) using

Indexed as

AstrocytesBrainGlutamic AcidGlutamineNeuronsTumor Necrosis Factor-alphaAcetatesAnimalsCarbon-13 Magnetic Resonance SpectroscopyCarbon IsotopesCitric Acid CycleGlucoseGlycolysisLactic AcidMalePentose Phosphate PathwayAcetatesCarbon IsotopesGlucoseGlutamic AcidGlutamineLactic AcidPyruvate CarboxylaseTumor Necrosis Factor-alphaastrocyteex-vivo NMRmetabolomicsneuroinflammationstable isotope tracingtumor necrosis factor

Identifiers

PMID38943617
PMCPMC11301676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.