Evidence map›Paper›PMID 38943538›Full record

ArticleGeriatrics & gerontology international2024

Identifying factors associated with locomotive syndrome using machine learning methods: The third survey of the research on osteoarthritis/osteoporosis against disability study.

Eri Nakahara, Toshiko Iidaka, Akihiro Chiba, Hisashi Kurasawa, Akinori Fujino, Nagisa Shiomi, Hirohito Maruyama, Chiaki Horii, Shigeyuki Muraki, Hiroyuki Oka and 5 more

Abstract read
In one paragraph

Article in Geriatrics & gerontology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Eri NakaharaNTT Basic Research Laboratories, Bio-Medical Informatics Research Center, Atsugi-shi, Japan.ORCID https://orcid.org/0000-0002-0199-3249
Toshiko IidakaDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Akihiro ChibaNTT Basic Research Laboratories, Bio-Medical Informatics Research Center, Atsugi-shi, Japan.ORCID https://orcid.org/0000-0002-3110-2048
Hisashi KurasawaNTT Computer and Data Science Laboratories, Tokyo, Japan.
Akinori FujinoNTT Basic Research Laboratories, Bio-Medical Informatics Research Center, Atsugi-shi, Japan.
Nagisa ShiomiNTT Basic Research Laboratories, Bio-Medical Informatics Research Center, Atsugi-shi, Japan.
Hirohito MaruyamaDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Chiaki HoriiDepartment of Orthopedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Shigeyuki MurakiDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Hiroyuki OkaDepartment of Medical Research and Management for Musculoskeletal Pain 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Hiroshi KawaguchiNadogaya Hospital, Kashiwa-shi, Japan.
Kozo NakamuraTowa Hospital, Tokyo, Japan.
Toru AkuneNational Rehabilitation Center for Persons with Disabilities, Tokorosawa-shi, Japan.
Sakae TanakaDepartment of Orthopedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Noriko YoshimuraDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.

Funding

Japan Agency for Medical Research and Development 17dk0110028h0001Japan Agency for Medical Research and Development 17gk0210007h0003Japan Agency for Medical Research and Development 19gk0210018h0002Japan Agency for Medical Research and Development 22dk0110047h0001Japan Society for the Promotion of Science 08033011-00262Japan Society for the Promotion of Science 15K15219Japan Society for the Promotion of Science 18K18447Japan Society for the Promotion of Science 21659349Japan Society for the Promotion of Science 21K19291Japan Society for the Promotion of Science 23659580Japan Society for the Promotion of Science 24659317Japan Society for the Promotion of Science 24659666Japan Society for the Promotion of Science 25670293Japan Society for the Promotion of Science 26670307Japan Society for the Promotion of Science A18689031Japan Society for the Promotion of Science B18H03164Japan Society for the Promotion of Science B19H03895Japan Society for the Promotion of Science B20390182Japan Society for the Promotion of Science B23390172Japan Society for the Promotion of Science B23390356Japan Society for the Promotion of Science B23390357Japan Society for the Promotion of Science B26293139Japan Society for the Promotion of Science B26293329Japan Society for the Promotion of Science B26293331Japan Society for the Promotion of Science C18K09122Japan Society for the Promotion of Science C20591737Japan Society for the Promotion of Science C20591774Japan Society for the Promotion of Science S50282661the Ministry of Health, Labour and Welfare 19FA0701the Ministry of Health, Labour and Welfare 19FA1401the Ministry of Health, Labour and Welfare 19FA1901the Ministry of Health, Labour and Welfare 19FB1001the Ministry of Health, Labour and Welfare 20JA1001the Ministry of Health, Labour and Welfare 21FA1006the Ministry of Health, Labour and Welfare 22FA1009the Ministry of Health, Labour and Welfare 24FA1006the Ministry of Health, Labour and Welfare H17-Men-eki-009the Ministry of Health, Labour and Welfare H20-Choujyu-009the Ministry of Health, Labour and Welfare H23-Choujyu-002the Ministry of Health, Labour and Welfare H25-Choujyu-007the Ministry of Health, Labour and Welfare H25-Nanchitou (Men)-005
6 · The paper itself

Abstract

aimTo identify factors associated with locomotive syndrome (LS) using medical questionnaire data and machine learning.

methodsA total of 1575 participants underwent the LS risk tests from the third survey of the research on osteoarthritis/osteoporosis against disability study (ROAD) study. LS was defined as stage 1 or higher based on clinical decision limits of the Japanese Orthopaedic Association. A total of 1335 items of medical questionnaire data came from this study. The number of medical questionnaire items was reduced from 1335 to 331 in data cleaning. From the 331 items, identify factors associated with LS use by light gradient boosting machine-based recursive feature elimination with cross-validation. The performance of each set was evaluated using an average of seven performance metrics, including 95% confidence intervals, using a bootstrapping method. The smallest set of items is determined with the highest average of receiver operating characteristic area under the curve (ROC-AUC) under 20 items as association factors of LS. Additionally, the performance of the selected items was compared with the LS risk tests and Loco-check.

resultsThe nine items have the best average ROC-AUC under 20 items. The nine items show an average ROC-AUC of 0.858 (95% confidence interval 0.816-0.898). Age and back pain during walking were strongly associated with the prevalence of LS. The ROC-AUC of nine items is higher than that of existing questionnaire-based LS assessments, including the 25-question Geriatric Locomotor Scale and Loco-check.

conclusionsThe identified nine items could aid early LS detection, enhancing understanding and prevention. Geriatr Gerontol Int 2024; 24: 806-813.

Indexed as

Machine LearningAgedAged, 80 and overDisability EvaluationFemaleHumansJapanLocomotionMaleMiddle AgedMobility LimitationOsteoarthritisOsteoporosisRisk AssessmentRisk FactorsROC Curveassociated factorcohort studylocomotive syndromemachine learningprevalence

Identifiers

PMID38943538
PMCPMC11503583

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.