Evidence map›Paper›PMID 38943397›Full record

ArticleJournal of Parkinson's disease2024

Rapid Voluntary Blinking as a Clinical Marker of Parkinson's Disease.

Michaela Francis, Alexandra Zirra, Tahrina Haque, David Gallagher, Caroline Budu, Andrew J Lees, Anette Schrag, Alastair J Noyce, Cristina Simonet

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michaela FrancisCentre for Preventive Neurology, Wolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Alexandra ZirraCentre for Preventive Neurology, Wolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Tahrina HaqueThe Royal London Hospital, Barts Health NHS Trust, London, UK.
David GallagherThe Royal London Hospital, Barts Health NHS Trust, London, UK.
Caroline BuduThe Royal London Hospital, Barts Health NHS Trust, London, UK.
Andrew J LeesReta Lila Weston Institute of Neurological Studies, University College London Queen Square Institute of Neurology, London, UK.
Anette SchragDepartment of Clinical and Movement Neuroscience, UCL Institute of Neurology, London, UK.
Alastair J NoyceCentre for Preventive Neurology, Wolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Cristina SimonetCentre for Preventive Neurology, Wolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduced spontaneous blinking is a recognized Parkinson's disease (PD) feature. In contrast, voluntary blinking has been less studied and might serve as a measurable marker of facial bradykinesia. We tested 31 PD patients and 31 controls. Participants were filmed during conversation and a rapid blinking task. Both tasks were videorecorded to count the number of blinks per second. PD patients had lower blink rates. Rapid blinking accurately discriminated between groups with 77% sensitivity and 71% specificity. To conclude, rapid blinking may be a simple and quantifiable task of facial bradykinesia.

Indexed as

BlinkingParkinson DiseaseAgedFemaleHumansHypokinesiaMaleMiddle AgedBlinkingbradykinesiahypomimiaParkinson’s disease

Identifiers

PMID38943397
PMCPMC11307067

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.