Evidence map›Paper›PMID 38943222›Full record

ReviewEuropean journal of medical research2024

Therapeutic potential of extracellular vesicles from diverse sources in cancer treatment.

Haihong Lin, Jun Zhou, Tao Ding, Yifan Zhu, Lijuan Wang, Tianyu Zhong, Xiaoling Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Emerging Biomimetic Drug Delivery Nanoparticles Inspired by Extracellular Vesicles.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haihong Lin *The First School of Clinical Medicine, Gannan Medical University, Ganzhou, 341000, China.
Jun Zhou *Department of Laboratory Medicine, Beijing Jishuitan Hospital Guizhou Hospital, Guiyang, 550000, China.
Tao DingLaboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China.
Yifan ZhuThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, 341000, China.
Lijuan WangThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, 341000, China.
Tianyu ZhongThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, 341000, China. zhongtianyu@gmail.com.
Xiaoling WangThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, 341000, China. wangxiaoling1@gmu.cn.

Funding

Municipal level scientific research plan project of Ganzhou Municipal Health Commission 2022-2-62Science and Technology Plan of Jiangxi Provincial Administration of Traditional Chinese Medicine 2022B495Science and Technology Plan of Jiangxi Provincial Health Commission 202210863
6 · The paper itself

Abstract

Cancer, a prevalent and complex disease, presents a significant challenge to the medical community. It is characterized by irregular cell differentiation, excessive proliferation, uncontrolled growth, invasion of nearby tissues, and spread to distant organs. Its progression involves a complex interplay of several elements and processes. Extracellular vesicles (EVs) serve as critical intermediaries in intercellular communication, transporting critical molecules such as lipids, RNA, membrane, and cytoplasmic proteins between cells. They significantly contribute to the progression, development, and dissemination of primary tumors by facilitating the exchange of information and transmitting signals that regulate tumor growth and metastasis. However, EVs do not have a singular impact on cancer; instead, they play a multifaceted dual role. Under specific circumstances, they can impede tumor growth and influence cancer by delivering oncogenic factors or triggering an immune response. Furthermore, EVs from different sources demonstrate distinct advantages in inhibiting cancer. This research examines the biological characteristics of EVs and their involvement in cancer development to establish a theoretical foundation for better understanding the connection between EVs and cancer. Here, we discuss the potential of EVs from various sources in cancer therapy, as well as the current status and future prospects of engineered EVs in developing more effective cancer treatments.

Indexed as

Extracellular VesiclesNeoplasmsAnimalsCell CommunicationHumansCancerCancer therapyEngineered extracellular vesiclesExtracellular vesiclesTherapeutic vehicles

Identifiers

PMID38943222
PMCPMC11212438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.