Evidence map›Paper›PMID 38942957›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2024

Applications of functional neurotransmitter release imaging with genetically encoded sensors in psychiatric research.

Emily C Wright, Erin Scott, Lin Tian

Erratum issuedAbstract readReview
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Genetically encoded sensors illuminateIBRO neuroscience reports · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Emily C WrightMax Planck Florida Institute for Neuroscience, Jupiter, FL, USA. emily.wright@mpfi.org.ORCID 0000-0001-9083-7864
Erin ScottMax Planck Florida Institute for Neuroscience, Jupiter, FL, USA.
Lin TianMax Planck Florida Institute for Neuroscience, Jupiter, FL, USA. lin.tian@mpfi.org.

Funding

Multiplex interrogation of neuromodulatory signaling in behaving animals with enhanced depth and resolutionU01NS120820 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TIAN, LIN, VONZASTROW, MARK E · 2021 to 2024
$3.5M
Imaging Dynamics in Anxiogenic Serotonin CircuitryF32MH125597 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WRIGHT, EMILY CLARISSA · 2021 to 2024
$225k
U.S. Department of Health & Human Services | National Institutes of Health (NIH) F32MH125597U.S. Department of Health & Human Services | National Institutes of Health (NIH) U01NS120820U.S. Department of Health & Human Services | National Institutes of Health (NIH) U19NS1237190U.S. Department of Health & Human Services | National Institutes of Health (NIH) UF1MH28336
6 · The paper itself

Abstract

Psychiatric research encompasses diverse methodologies to understand the complex interplay between neurochemistry and behavior in mental health disorders. Despite significant advancements in pharmacological interventions, there remains a critical gap in understanding the precise functional changes underlying psychiatric conditions and the mechanisms of action of therapeutic agents. Genetically encoded sensors have emerged as powerful tools to address these challenges by enabling real-time monitoring of neurochemical dynamics in specific neuronal populations. This prospective explores the utility of neurotransmitter binding genetically encoded sensors in uncovering the nature of neuronal dysregulation underpinning mental illness, assessing the impact of pharmaceutical interventions, and facilitating the discovery of novel treatments.

Indexed as

Mental DisordersNeurotransmitter AgentsAnimalsBiosensing TechniquesHumansNeurotransmitter Agents

Identifiers

PMID38942957
PMCPMC11525779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.