SynthesisKorean journal of radiology2024
Diffusion-Weighted MRI for the Assessment of Molecular Prognostic Biomarkers in Breast Cancer.
Synthesis in Korean journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic Test Accuracy of Apparent Diffusion Coefficient in Evaluation of Breast Cancer Lymph Node Metastasis: A Systematic Review and Meta-Analysis.Cancer reports (Hoboken, N.J.) · 2025Pooled it
- Feasibility of predicting breast cancer Ki-67 expression using histogram features derived from time-dependent diffusion magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2026Article
- Added value of intravoxel incoherent motion histogram analysis in differentiating HER2-zero, HER2-low, and HER2-positive breast cancer.La Radiologia medica · 2026Article
- Distinguishing Ki67 stratification expression in ER-positive/HER2-negative breast cancers: comparison of advanced MRI diffusion models.BMC medical imaging · 2026Article
- ADC Histogram Features of Breast Cancer Brain Metastases as Candidate Imaging Biomarkers of Primary Tumor ER, PR, Ki-67, and Luminal Status.Diagnostics (Basel, Switzerland) · 2026Article
- Time-dependent diffusion MRI of soft tissue tumors: correlations with Ki-67 proliferation status.Quantitative imaging in medicine and surgery · 2026Article
- Integrating time-dependent diffusion MRI and intravoxel incoherent motion for predicting NPI and molecular subtypes in breast cancer.BMC medical imaging · 2026Article
- A novel biomarker for identifying HER2-low breast cancer using synthetic MRI.Scientific reports · 2025Article
- Multimodal imaging and advanced quantitative techniques for HER-2 status prediction in breast cancer.Discover oncology · 2025Review
- Breast Diffusion-weighted MR Imaging: Current Applications, Insights from Screening, and Future Directions.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Review
- Dual-Time-Point Radiomics for Prognosis Prediction in Colorectal Liver Metastasis Treated with Neoadjuvant Therapy Before Radical Resection: A Two-Center Study.Annals of surgical oncology · 2025Article
- Standardization and advancements efforts in breast diffusion-weighted imaging.Japanese journal of radiology · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This study systematically reviewed the role of diffusion-weighted imaging (DWI) in the assessment of molecular prognostic biomarkers in breast cancer, focusing on the correlation of apparent diffusion coefficient (ADC) with hormone receptor status and prognostic biomarkers. Our meta-analysis includes data from 52 studies examining ADC values in relation to estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), and Ki-67 status. The results indicated significant differences in ADC values among different receptor statuses, with ER-positive, PgR-positive, HER2-negative, and Ki-67-positive tumors having lower ADC values compared to their negative counterparts. This study also highlights the potential of advanced DWI techniques such as intravoxel incoherent motion and non-Gaussian DWI to provide additional insights beyond ADC. Despite these promising findings, the high heterogeneity among the studies underscores the need for standardized DWI protocols to improve their clinical utility in breast cancer management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.