Evidence map›Paper›PMID 38941455›Full record

ArticleScience advances2024

Regulation of blood-brain barrier integrity by

Delin Liu, Peng Liao, Hao Li, Sihan Tong, Bingqi Wang, Yafei Lu, Youshui Gao, Yigang Huang, Hao Zhou, Linjing Shi and 10 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  4. Xenogeneic Mitochondrial Transplantation Improves Selected Age-Associated Phenotypes in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Delin LiuCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.ORCID 0009-0006-6239-1950
Peng LiaoDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.ORCID 0000-0002-4583-5285
Hao LiDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Sihan TongDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Bingqi WangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Yafei LuDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Youshui GaoDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.ORCID 0000-0001-9242-2486
Yigang HuangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Hao ZhouDepartment of Orthopaedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province 310009, China.ORCID 0000-0002-5801-833X
Linjing ShiDepartment of Orthopaedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province 310009, China.
John PapadimitriouCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.
Yao ZongCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.
Jun YuanCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.ORCID 0000-0001-6542-4654
Peilin ChenCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.
Ziming ChenCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.
Peng DingDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.ORCID 0000-0002-9348-8134
Yongqiang ZhengDepartment of Orthopaedics, Jinjiang Municipal Hospital, Jinjiang, Fujian Province, 362200, China.
Changqing ZhangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.ORCID 0000-0002-7408-4126
Minghao ZhengCentre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia 6009, Australia.ORCID 0000-0003-1185-4768
Junjie GaoDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.ORCID 0000-0003-4820-8524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The blood-brain barrier (BBB) acts as the crucial physical filtration structure in the central nervous system. Here, we investigate the role of a specific subset of astrocytes in the regulation of BBB integrity. We showed that

Indexed as

AstrocytesBlood-Brain BarrierEndothelial CellsMitochondriaAnimalsGTP PhosphohydrolasesMiceGTP PhosphohydrolasesMfn2 protein, mouse

Identifiers

PMID38941455
PMCPMC11212732

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.