Evidence map›Paper›PMID 38940852›Full record

ArticleCurrent microbiology2024

Deciphering the Antibiofilm, Antibacterial, and Antioxidant Potential of Essential Oil from Indian Garlic and its Phytocompounds Against Foodborne Pathogens.

Ashirbad Sarangi, Bhabani Shankar Das, Ambika Sahoo, Biswajit Jena, Gautam Patnaik, Sidhartha Giri, Debprasad Chattopadhyay, Debapriya Bhattacharya

Abstract read
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In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashirbad Sarangi *Centre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, India.
Bhabani Shankar Das *Centre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, India.
Ambika SahooCentre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, India.
Biswajit JenaCentre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, India.
Gautam PatnaikSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Sidhartha GiriICMR-Regional Medical Research Centre (RMRC), Bhubaneswar, Odisha, India.
Debprasad ChattopadhyayICMR-National Institute of Traditional Medicine, Belagavi, Karnataka, 590010, India. debprasadc@yahoo.co.in.ORCID http://orcid.org/0000-0002-7999-329X
Debapriya BhattacharyaCentre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, India. debapriyabhattacharyab@gmail.com.ORCID http://orcid.org/0000-0003-2732-6599

Funding

Science and Engineering Research Board SRG/2020/001922University Grants Commission No.F.30-523/2021 (BSR) FD Diary No. 2183
6 · The paper itself

Abstract

Garlic (Allium sativum L.), particularly its volatile essential oil, is widely recognized for medicinal properties. We have evaluated the efficacy of Indian Garlic Essential Oil (GEO) for antimicrobial and antibiofilm activity and its bioactive constituents. Allyl sulfur-rich compounds were identified as predominant phytochemicals in GEO, constituting 96.51% of total volatile oils, with 38% Diallyl trisulphide (DTS) as most abundant. GEO exhibited significant antibacterial activity against eleven bacteria, including three drug-resistant strains with minimum inhibitory concentrations (MICs) ranging from 78 to 1250 µg/mL. In bacterial growth kinetic assay GEO effectively inhibited growth of all tested strains at its ½ MIC. Antibiofilm activity was evident against two important human pathogens, S. aureus and P. aeruginosa. Mechanistic studies demonstrated that GEO disrupts bacterial cell membranes, leading to the release of nucleic acids, proteins, and reactive oxygen species. Additionally, GEO demonstrated potent antioxidant activity at IC

Indexed as

Anti-Bacterial AgentsAntioxidantsBiofilmsGarlicMicrobial Sensitivity TestsOils, VolatileAllyl CompoundsBacteriaDisulfidesHumansIndiaPhytochemicalsPlant ExtractsPlant OilsPseudomonas aeruginosaStaphylococcus aureusAllyl CompoundsAnti-Bacterial AgentsAntioxidantsdiallyl trisulfideDisulfidesOils, VolatilePhytochemicalsPlant ExtractsPlant OilsSulfides

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.