Evidence map›Paper›PMID 38940842›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2024

Whole-body parametric mapping of tumour perfusion in metastatic prostate cancer using long axial field-of-view [

Mads Ryø Jochumsen, Nana L Christensen, Peter Iversen, Lars C Gormsen, Jens Sørensen, Lars P Tolbod

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Quantitative Total-Body Imaging of Blood Flow with High-Temporal-Resolution Early DynamicJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mads Ryø JochumsenDepartment of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, Aarhus N, 8200, Denmark. madsjoch@rm.dk.ORCID 0000-0002-7676-2322
Nana L ChristensenDepartment of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, Aarhus N, 8200, Denmark.
Peter IversenDepartment of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, Aarhus N, 8200, Denmark.
Lars C GormsenDepartment of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, Aarhus N, 8200, Denmark.
Jens SørensenDepartment of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, Aarhus N, 8200, Denmark.
Lars P TolbodDepartment of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, Aarhus N, 8200, Denmark.

Funding

Else og Mogens Wedell Wedellsborgs Fond 5- 20 - 2Fabrikant Einar Willumsens Mindelegat 500028NEYE-Fonden NEYE-FondenNovo Nordisk Fonden NNF19OC0055100P. A. Messerschmidt og Hustrus Fond 028077-0006Tømrermester Jørgen Holm og hustru Elisa f. Hansens Mindelegat 20006-1937
6 · The paper itself

Abstract

purposeTumour perfusion is a nutrient-agnostic biomarker for cancer metabolic rate. Use of tumour perfusion for cancer growth assessment has been limited by complicated image acquisition, image analysis and limited field-of-view scanners. Long axial field-of-view (LAFOV) PET scan using [

methodsTen metastatic prostate cancer patients underwent dynamic LAFOV [

resultsFor 8 primary tumours, 64 lymph node metastases, and 85 bone metastases, median tumour perfusion were 0.19 (0.15-0.27) mL/min/mL, 0.16 (0.13-0.27) mL/min/mL, and 0.26 (0.21-0.39), respectively. The correlation between calculated perfusion from time-activity-curves and parametric images was excellent (r = 0.99, p < 0.0001).

conclusionLAFOV PET imaging using [

Indexed as

Neoplasm MetastasisPositron-Emission TomographyProstatic NeoplasmsAgedHumansMaleMiddle AgedOxygen RadioisotopesPerfusion ImagingWhole Body ImagingOxygen RadioisotopesCancerDynamic PETLong axial field-of-viewPerfusionProstate cancerTumour blood flow

Identifiers

PMID38940842
PMCPMC11527927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.