Evidence map›Paper›PMID 38940687›Full record

ArticleClinical transplantation and research2024

Perioperative optic nerve sheath diameter variations in patients with end-stage renal failure undergoing robotic-assisted kidney transplant: a prospective observational study.

Nisha Rajmohan, Jithendra Thiruvathtra, Shilpa Omkarappa, Sangeeth Perath Srinivasan, Nidhin Eldo, Rajesh Rajgopal

Abstract read
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Article in Clinical transplantation and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nisha RajmohanDepartment of Anesthesia and Critical Care, Aster Medcity, Kochi, India.ORCID https://orcid.org/0000-0003-1389-179X
Jithendra ThiruvathtraDepartment of Anesthesia and Critical Care, Aster Medcity, Kochi, India.ORCID https://orcid.org/0000-0002-8595-502X
Shilpa OmkarappaDepartment of Anesthesia and Critical Care, Aster Medcity, Kochi, India.ORCID https://orcid.org/0000-0003-2407-9561
Sangeeth Perath SrinivasanDepartment of Anesthesia and Critical Care, Aster Medcity, Kochi, India.ORCID https://orcid.org/0000-0002-9365-2125
Nidhin EldoDepartment of Anesthesia and Critical Care, Aster Medcity, Kochi, India.ORCID https://orcid.org/0000-0002-5387-0902
Rajesh RajgopalDepartment of Anesthesia and Critical Care, Aster Medcity, Kochi, India.ORCID https://orcid.org/0000-0003-2447-932X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with chronic kidney disease (CKD) who undergo hemodialysis are predisposed to interstitial cerebral edema. Robotic-assisted laparoscopic surgery can increase optic nerve sheath diameter (ONSD) and intracranial pressure. The impact of robotic-assisted kidney transplant (RAKT) on ONSD is complicated by the presence of CKD, the administration of furosemide and mannitol, and the manipulation of hemodynamics. We examined ONSD variations in patients undergoing RAKT over a 1-year period at our institution. Furthermore, we attempted to identify any perioperative hemodynamic factors influencing these changes. Methods: This prospective study included 20 patients undergoing RAKT. ONSD, heart rate, central venous pressure, systolic blood pressure, diastolic blood pressure (DBP), and mean arterial pressure (MAP) were measured following intubation (T1), after assuming the steep Trendelenburg position (T2), 1 hour after docking (T3), upon reperfusion (T4), after transition to the supine position (T5), and 3 hours postextubation (T6). Repeated measures analysis of variance with post hoc Bonferroni correction was employed to compare variables at each time point. Pearson correlation analysis was utilized to assess relationships between variables. P-values ≤0.05 were considered to indicate statistical significance. Results: ONSD (in mm) increased from T1 (3.60±0.44) to T3 (4.06±0.45, P=0.002) and T4 (3.99±0.62, P=0.046), before falling to its lowest value at T6 (3.42±0.64, P=0.002). Pearson correlation analysis revealed significant correlations (P<0.05) between changes in ONSD at T3 and both DBP (r=0.637) and MAP (r=0.522). Conclusions: During RAKT with open ureteric anastomosis, ONSD initially increased, then decreased following reperfusion. DBP and MAP displayed positive correlations with ONSD changes at T3.

Indexed as

Elevated intracranial pressureKidney transplantationsPneumoperitoneumRobotic-assisted surgeryTrendelenburg position

Identifiers

PMID38940687
PMCPMC11228382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.