Evidence map›Paper›PMID 38940570›Full record

ArticleAntimicrobial agents and chemotherapy2024

The intrinsic macrolide resistome of

Yibing Ma, Mattia Pirolo, Bimal Jana, Viktor Hundtofte Mebus, Luca Guardabassi

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Reporting macrolide-resistantJournal of clinical microbiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. High-level multidrug resistance and an unexpected mecA gene detection in Vibrio spp. from Litopenaeus vannamei aquaculture in Vietnam.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. The Secondary Resistome of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  18. Macrolide resistance inFrontiers in cellular and infection microbiology · 2025
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yibing MaDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.ORCID 0009-0002-0143-7477
Mattia PiroloDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0002-9814-1500
Bimal JanaCenter for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Viktor Hundtofte MebusDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.
Luca GuardabassiDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0002-2389-5084

Funding

EC | Horizon Europe | Excellent Science | HORIZON EUROPE Marie Sklodowska-Curie Actions (MSCA) 956154
6 · The paper itself

Abstract

Intrinsic resistance to macrolides in Gram-negative bacteria is primarily attributed to the low permeability of the outer membrane, though the underlying genetic and molecular mechanisms remain to be fully elucidated. Here, we used transposon directed insertion-site sequencing (TraDIS) to identify chromosomal non-essential genes involved in

Indexed as

Escherichia coliGenes, BacterialMacrolidesBacterial Outer MembraneDNA Transposable ElementsGenome-Wide Association StudyLipopolysaccharidesMutagenesis, InsertionalSequence Analysis, DNADNA Transposable ElementsLipopolysaccharidesMacrolidesE. coliintrinsic resistancemacrolidetilmicosinTraDIS

Identifiers

PMID38940570
PMCPMC11304742

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.