Evidence map›Paper›PMID 38940507›Full record

ArticlemSphere2024

Probing gene function in

Bernardo Ramírez-Zavala, Anna Hoffmann, Ines Krüger, Sonja Schwanfelder, Katherine S Barker, P David Rogers, Joachim Morschhäuser

Abstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bernardo Ramírez-ZavalaInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Anna HoffmannInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Ines KrügerInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Sonja SchwanfelderInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Katherine S BarkerDepartment of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
P David RogersDepartment of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Joachim MorschhäuserInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.ORCID 0000-0003-4227-8687

Funding

Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8M
Novel Azole Resistance Mechanisms in Candida albicansR21AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P DAVID · 2004 to 2004
$292k
NIAID NIH HHS R01 AI058145NIAID NIH HHS R21 AI058145
6 · The paper itself

Abstract

The adaptation of gene deletion methods based on the CRISPR-Cas9 system has facilitated the genetic manipulation of the pathogenic yeast IMPORTANCE:

Indexed as

Candida albicansCRISPR-Cas SystemsLoss of HeterozygosityRecombination, GeneticAntifungal AgentsCRISPR-Associated Protein 9Drug Resistance, FungalFluconazoleGene DeletionGene EditingGenetic MarkersHygromycin BStreptothricinsAntifungal AgentsCRISPR-Associated Protein 9FluconazoleGenetic MarkersHygromycin BStreptothricinsCandida albicansCRISPR-Cas9gene deletionhomozygous mutantsloss of heterozygosity

Identifiers

PMID38940507
PMCPMC11288041

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.