Evidence map›Paper›PMID 38940477›Full record

ReviewMovement disorders clinical practice2024

A Critical Examination of the Clinical Diagnosis of Functional Tic-like Behaviors.

Kaja Andersen, Andrea Eugenio Cavanna, Natalia Szejko, Kirsten R Müller-Vahl, Tammy Hedderly, Liselotte Skov, Nanette Mol Debes

Abstract readReview
In one paragraph

Review in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaja AndersenDepartment of Pediatrics, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.ORCID https://orcid.org/0000-0002-9667-9497
Andrea Eugenio CavannaDepartment of Neuropsychiatry, BSMHFT and University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0003-0925-1255
Natalia SzejkoDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-6160-9221
Kirsten R Müller-VahlDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-7181-7419
Tammy HedderlyGuys and St Thomas Hospital and KCL Faculty of Life Sciences and Medicine, Evelina London Children's Hospital, London, UK.ORCID https://orcid.org/0000-0002-5467-054X
Liselotte SkovDepartment of Pediatrics, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.ORCID https://orcid.org/0000-0002-2137-0735
Nanette Mol DebesDepartment of Pediatrics, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.ORCID https://orcid.org/0000-0003-0279-1865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the COVID-19 pandemic, movement disorder clinics have seen an increase in patients with an unusual type of tic-like symptoms: young adults with abrupt onset complex behaviors. It was quickly suspected that these patients suffered from functional neurological symptoms, later named Functional Tic-Like Behaviors (FTLB). Subsequent research on the differential diagnosis between FTLB and tics has been substantial and led to the development of diagnostic checklists.

objectivesWe conducted a theoretical reappraisal of the FTLB literature to clarify the validity of the concept and its diagnostic implications.

methodsThis paper addresses several key aspects of the current FTLB literature: circular reasoning, the complications of the FTLB phenomenology and demographics, the impact of FTLB on tic literature at large, and issues with alignment of the FTLB concept with the diagnostic criteria for functional disorders.

resultsThe clinical approach to FTLB might involve circular reasoning due to a lack of clinical benchmarks. The FTLB phenomenology and demographics may need more work to ensure a lack of bias and a proper description of this patient group including a clear distinction from tics. The impact of the FTLB discussion on the wider literature needs consideration. The validation of positive signs may help with both these endeavors and pave way to the inclusion of FTLB within psychiatric classification systems. Furthermore, the coexistence of FTLB and tics within the same patient needs to be addressed.

conclusionMore research may be needed to fully establish the diagnosis of FTLB and differentiate it from tics.

Indexed as

COVID-19Tic DisordersDiagnosis, DifferentialHumansTicsfunctional neurological disordersfunctional tic‐like behaviorstic disordersTourette's syndrome

Identifiers

PMID38940477
PMCPMC11452787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.