Evidence map›Paper›PMID 38940398›Full record

ArticleHistology and histopathology2024

S100A2 upregulates GLUT1 expression to promote glycolysis in the progression of nasopharyngeal carcinoma.

Ying Peng, Jing Xia, Dinggang Zhou, Zhongchun Yang, Ruifang Zeng, Min Xu, Hongwei Peng

Abstract read
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In one paragraph

Article in Histology and histopathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying PengDepartment of Otolaryngology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Jing XiaENT Teaching and Research Section, Department of Stomatology, Changsha Health Vocational College, Changsha, Hunan, China.
Dinggang ZhouDepartment of Otolaryngology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Zhongchun YangDepartment of Otolaryngology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Ruifang ZengDepartment of Otolaryngology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Min XuDepartment of Otolaryngology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Hongwei PengDepartment of Nursing, Hunan Nursing School, Changsha, Hunan, China. pzc0731@163.com.

Funding

Hunan Provincial Health Commission 202107010061Hunan Provincial Health Commission 202107011050
6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor. Among the S100 protein family members, the imbalance of S100 calcium-binding protein A2 (S100A2) was related to the pathogenesis of several types of cancer, and S100A2 has been reported to be upregulated in the plasma of NPC patients; however, its specific role in NPC pathogenesis remains unclear. Thus, this study aims to determine the potential role of S100A2 in NPC to provide novel insights into NPC management. C666-1 and NPC/HK-1 cells were transfected with S100A2 silencing/overexpression (si/oe) constructs. For

Indexed as

Glucose Transporter Type 1GlycolysisMice, NudeNasopharyngeal CarcinomaNasopharyngeal NeoplasmsS100 ProteinsUp-RegulationAnimalsApoptosisCell Line, TumorCell ProliferationChemotactic FactorsDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansChemotactic FactorsGlucose Transporter Type 1S100A2 protein, humanS100 ProteinsSLC2A1 protein, human

Identifiers

PMID38940398

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.