Evidence map›Paper›PMID 38939903›Full record

ArticleJournal of extracellular biology2024

Anti-cancer bioactivity of sweet basil leaf derived extracellular vesicles on pancreatic cancer cells.

Uday Chintapula, Daniel Oh, Cristina Perez, Sachin Davis, Jina Ko

Abstract read
In one paragraph

Article in Journal of extracellular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  10. Article
  11. Extracellular Vesicle-Based Drug Delivery Systems in Cancer Therapy.International journal of molecular sciences · 2025
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Uday ChintapulaDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.
Daniel OhDepartment of Bioengineering, School of Engineering and Applied Sciences University of Pennsylvania Philadelphia Pennsylvania USA.
Cristina PerezDepartment of Bioengineering, School of Engineering and Applied Sciences University of Pennsylvania Philadelphia Pennsylvania USA.
Sachin DavisDepartment of Bioengineering, School of Engineering and Applied Sciences University of Pennsylvania Philadelphia Pennsylvania USA.
Jina KoDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.ORCID https://orcid.org/0000-0002-4941-4234

Funding

TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 1997 to 2026
$32.5M
NIDDK NIH HHS P30 DK050306
6 · The paper itself

Abstract

Most living organisms secrete tiny lipid bilayer particles encapsulating various biomolecular entities, including nucleic acids and proteins. These secreted extracellular vesicles (EVs) are shown to aid in communication between cells and their environment. EVs are mainly involved in the signalling and manipulation of physiological processes. Plant EVs display similar functional activity as seen in mammalian EVs. Medicinal plants have many bioactive constituents with potential applications in cancer treatment. Particularly, Basil (

Indexed as

anti‐cancerbasil plantextracellular vesiclespancreatic cancertherapeutics

Identifiers

PMID38939903
PMCPMC11080924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.